What is the reference range for 25-Hydroxyvitamin D3?

The standard reference range for 25-Hydroxyvitamin D3 is Varies by assay; typically accounts for the majority of total 25(OH)D in most populations.. Reference ranges vary by laboratory and assay platform — interpret in context of the issuing laboratory's stated range.

Which tests measure 25-Hydroxyvitamin D3?

25-Hydroxyvitamin D3 is measured in 1 test on BiomarkersLabs.com, including 25-Hydroxyvitamin D (D2, D3).

Biomarker Reference · 25(OH)D3

What does the 25-Hydroxyvitamin D3 test measure?

25-Hydroxyvitamin D3 (25(OH)D3) is a clinical biomarker used in vitamins-minerals assessment. D3 arises from endogenous synthesis in the skin under ultraviolet B exposure and from cholecalciferol in supplements and some fortified foods. It is measured in 1 laboratory test on BiomarkersLabs.com.

Reference Range: Varies by assay; typically accounts for the majority of total 25(OH)D in most populations.
Units: nmol/L, ng/mL
Measured In: 1 test
Category: Vitamins & Minerals

Functional medicine optimalNot independently defined; interpreted as part of total 25(OH)D.

What is 25-Hydroxyvitamin D3?

D3 arises from endogenous synthesis in the skin under ultraviolet B exposure and from cholecalciferol in supplements and some fortified foods. Its 25-hydroxylated metabolite has higher affinity for vitamin D-binding protein and a longer circulating half-life than the D2 form, making it the predominant contributor to total 25(OH)D in most individuals.

Why is 25-Hydroxyvitamin D3 measured?

Reporting D3 separately confirms the source and relative contribution of cholecalciferol to vitamin D status. Some evidence suggests D3 supplementation raises total 25(OH)D more efficiently than D2, though both forms correct deficiency. Like D2, it has no independent clinical threshold but is summed into total 25(OH)D for interpretation.

Reference ranges

Standard reference: Varies by assay; typically accounts for the majority of total 25(OH)D in most populations.
Functional medicine optimal: Not independently defined; interpreted as part of total 25(OH)D.
Units: nmol/L, ng/mL

Reference ranges vary by laboratory and assay platform. Interpret in context of the issuing laboratory's stated range.

Tests that measure 25-Hydroxyvitamin D3

1 test on BiomarkersLabs.com include this biomarker.

BML-VIT-024Comprehensive

25-Hydroxyvitamin D (D2, D3)

25-Hydroxyvitamin D3 reference range in this test: Varies by assay; typically accounts for the majority of total 25(OH)D in most populations.

Related clinical conditions

Related Biomarkers

Frequently measured alongside

25-Hydroxyvitamin D, Total25(OH)D1 test 25-Hydroxyvitamin D225(OH)D21 test

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