Biomarker Reference · B-Vitamins

What does the B-Vitamin Functional Status (e.g. B1, B2, B3, B6, B12, folate, biotin, pantothenate) test measure?

Q: What is the reference range for B-Vitamin Functional Status (e.g. B1, B2, B3, B6, B12, folate, biotin, pantothenate)?

The standard reference range for B-Vitamin Functional Status (e.g. B1, B2, B3, B6, B12, folate, biotin, pantothenate) is Reported as a functional classification (e.g. deficient / borderline / adequate) rather than a concentration # REVIEWER FLAG: SpectraCell reports functional intracellular status via a proprietary lymphocyte assay, not concentrations; reference classifications are proprietary — reviewer to confirm the exact analytes reported and how status is defined.. Reference ranges vary by laboratory and assay platform — interpret in context of the issuing laboratory's stated range.

B-Vitamin Functional Status (e.g. B1, B2, B3, B6, B12, folate, biotin, pantothenate) (B-Vitamins) is a clinical biomarker used in vitamins-minerals assessment. The B vitamins are cofactors in energy metabolism, one-carbon metabolism, and numerous enzymatic reactions. It is measured in 1 laboratory test on BiomarkersLabs.com.

Reference Range: Reported as a functional classification (e.g. deficient / borderline / adequate) rather than a concentration # REVIEWER FLAG: SpectraCell reports functional intracellular status via a proprietary lymphocyte assay, not concentrations; reference classifications are proprietary — reviewer to confirm the exact analytes reported and how status is defined.
Units: functional classification
Measured In: 1 test
Category: Vitamins & Minerals

Functional medicine optimalReported as 'adequate' on the functional classification; no numeric optimal value applies

What is B-Vitamin Functional Status (e.g. B1, B2, B3, B6, B12, folate, biotin, pantothenate)?

The B vitamins are cofactors in energy metabolism, one-carbon metabolism, and numerous enzymatic reactions. The SpectraCell method assesses functional intracellular status by measuring lymphocyte growth response under controlled nutrient conditions rather than measuring serum concentrations, and is claimed to reflect longer-term functional status over the lymphocyte lifespan. The panel reports a functional adequacy classification for each analyte.

Why is B-Vitamin Functional Status (e.g. B1, B2, B3, B6, B12, folate, biotin, pantothenate) measured?

Functional B-vitamin status is used in integrative and functional practice to identify intracellular deficiency that a practitioner may address with diet or supplementation. The approach is claimed to reflect function over months rather than recent intake, but its clinical validity and comparability with standard serum and functional markers (such as B12, folate, and methylmalonic acid) are debated, so results are interpreted as supportive rather than definitive.

Reference ranges

Standard reference: Reported as a functional classification (e.g. deficient / borderline / adequate) rather than a concentration # REVIEWER FLAG: SpectraCell reports functional intracellular status via a proprietary lymphocyte assay, not concentrations; reference classifications are proprietary — reviewer to confirm the exact analytes reported and how status is defined.
Functional medicine optimal: Reported as 'adequate' on the functional classification; no numeric optimal value applies
Units: functional classification

Reference ranges vary by laboratory and assay platform. Interpret in context of the issuing laboratory's stated range.

Tests that measure B-Vitamin Functional Status (e.g. B1, B2, B3, B6, B12, folate, biotin, pantothenate)

1 test on BiomarkersLabs.com include this biomarker.

BML-VIT-013Comprehensive

SpectraCell Micronutrient Test (Intracellular Functional Panel)

B-Vitamin Functional Status (e.g. B1, B2, B3, B6, B12, folate, biotin, pantothenate) reference range in this test: Reported as a functional classification (e.g. deficient / borderline / adequate) rather than a concentration # REVIEWER FLAG: SpectraCell reports functional intracellular status via a proprietary lymphocyte assay, not concentrations; reference classifications are proprietary — reviewer to confirm the exact analytes reported and how status is defined.

Related clinical conditions

Related Biomarkers

Frequently measured alongside

Total Antioxidant Function and Antioxidant Nutrients (e.g. SPECTROX, glutathione, CoQ10, selenium, vitamin E, cysteine, alpha-lipoic acid)Antioxidants1 test Mineral Functional Status (e.g. calcium, magnesium, zinc, copper, manganese)Minerals1 test Amino Acid and Metabolite Status (e.g. asparagine, glutamine, serine; carnitine, choline, inositol)Amino Acids / Metabolites1 test Carbohydrate Metabolism and Fatty Acid Status (e.g. chromium, glucose-insulin metabolism markers, oleic acid)Metabolic / Fatty Acid1 test Immune Response Index (proprietary; e.g. Immunidex)Immune Index1 test

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