What does the Borrelia burgdorferi sensu lato DNA test measure?

Why is Borrelia burgdorferi sensu lato DNA measured?

Direct detection of Borrelia DNA offers the possibility of confirming active infection without waiting for antibody seroconversion, particularly in the first few weeks after tick exposure when serological tests remain negative. Because bacteraemia is low-level and transient, sensitivity in whole blood is modest and varies by disease stage; detection is highest during early disseminated infection and drops sharply once the organism localises to tissue. A positive result confirms infection; a negative result does not exclude Lyme disease, and the test is adjunctive to serology and clinical assessment.

Reference ranges

Standard reference

Not detected

Functional medicine optimal

Not detected

Units

detected/not detected

Reference ranges vary by laboratory and assay platform. Interpret in context of the issuing laboratory's stated range.