Biomarker Reference · TcdB
Clostridium difficile Toxin B (TcdB) is a clinical biomarker used in gastrointestinal assessment. Toxin B is the more potent cytotoxin produced by toxigenic C. It is measured in 1 laboratory test on BiomarkersLabs.com.
Toxin B is the more potent cytotoxin produced by toxigenic C. difficile. Like toxin A, it inactivates Rho-family GTPases via glucosylation, causing cytoskeletal collapse, tight-junction disruption, and inflammatory cell infiltration. All pathogenic strains produce toxin B, making it an essential marker of infection.
Toxin B detection is the cornerstone of diagnosing C. difficile infection. This EIA offers a rapid faecal assay with high specificity; however, its moderate sensitivity means it is best used in combination with clinical criteria or followed by molecular testing in high-risk patients with a negative result.
Reference ranges vary by laboratory and assay platform. Interpret in context of the issuing laboratory's stated range.
1 test on BiomarkersLabs.com include this biomarker.
Available exclusively to verified licensed healthcare practitioners. CLIA-certified laboratory results delivered to your secure portal.
Create Free Account