What is the reference range for Cortisol at 16:00?

The standard reference range for Cortisol at 16:00 is Approximately 50–330 nmol/L (2–12 µg/dL) at 16:00, assay-specific.. Reference ranges vary by laboratory and assay platform — interpret in context of the issuing laboratory's stated range.

Which tests measure Cortisol at 16:00?

Cortisol at 16:00 is measured in 1 test on BiomarkersLabs.com, including Cortisol, 6 Specimens.

Biomarker Reference · 16:00 Cortisol

What does the Cortisol at 16:00 test measure?

Cortisol at 16:00 (16:00 Cortisol) is a clinical biomarker used in adrenal-stress assessment. The late-afternoon cortisol lies on the descending slope of the circadian curve, typically 40–60 per cent of the morning peak. It is measured in 1 laboratory test on BiomarkersLabs.com.

Reference Range: Approximately 50–330 nmol/L (2–12 µg/dL) at 16:00, assay-specific.
Units: nmol/L, µg/dL
Measured In: 1 test
Category: Adrenal

Functional medicine optimalLate-afternoon cortisol is generally 30–50 per cent of the morning peak, continuing the downward trend.

What is Cortisol at 16:00?

The late-afternoon cortisol lies on the descending slope of the circadian curve, typically 40–60 per cent of the morning peak. It provides an intermediate checkpoint before the evening nadir.

Why is Cortisol at 16:00 measured?

A 16:00 cortisol that remains high relative to the morning value suggests loss of diurnal rhythm, a hallmark of autonomous cortisol secretion. Conversely, an inappropriately low afternoon level in the setting of symptoms points to inadequate adrenal reserve.

Reference ranges

Standard reference: Approximately 50–330 nmol/L (2–12 µg/dL) at 16:00, assay-specific.
Functional medicine optimal: Late-afternoon cortisol is generally 30–50 per cent of the morning peak, continuing the downward trend.
Units: nmol/L, µg/dL

Reference ranges vary by laboratory and assay platform. Interpret in context of the issuing laboratory's stated range.

Tests that measure Cortisol at 16:00

1 test on BiomarkersLabs.com include this biomarker.

BML-ADR-033Comprehensive

Cortisol, 6 Specimens

Cortisol at 16:00 reference range in this test: Approximately 50–330 nmol/L (2–12 µg/dL) at 16:00, assay-specific.

Related clinical conditions

Related Biomarkers

Frequently measured alongside

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