Which tests measure Estimated Glomerular Filtration Rate (Cystatin C)?

Estimated Glomerular Filtration Rate (Cystatin C) is measured in 1 test on BiomarkersLabs.com, including Cystatin C with Glomerular Filtration Rate, Estimated (eGFR).

Biomarker Reference · eGFRcys

What does the Estimated Glomerular Filtration Rate (Cystatin C) test measure?

Q: Why is Estimated Glomerular Filtration Rate (Cystatin C) measured?

eGFRcys is a more accurate filtration marker in patients with sarcopaenia, obesity, limb amputation, chronic illness, or extremes of age. It detects earlier declines in kidney function and reclassifies a meaningful proportion of patients compared with creatinine eGFR alone. Combined creatinine–cystatin C equations (eGFRcr-cys) are now recommended by KDIGO when confirmatory testing is needed.

Q: What is the reference range for Estimated Glomerular Filtration Rate (Cystatin C)?

The standard reference range for Estimated Glomerular Filtration Rate (Cystatin C) is ≥90 mL/min/1.73 m² is stage G1 (normal or high); 60–89 is G2 (mildly decreased); 45–59 is G3a; 30–44 is G3b; 15–29 is G4 (severely decreased); <15 is G5 (kidney failure).. Reference ranges vary by laboratory and assay platform — interpret in context of the issuing laboratory's stated range.

Estimated Glomerular Filtration Rate (Cystatin C) (eGFRcys) is a clinical biomarker used in kidney-renal assessment. The eGFRcys is calculated from serum cystatin C, age, and sex using the CKD-EPI 2012 cystatin C equation. It is measured in 1 laboratory test on BiomarkersLabs.com.

Reference Range: ≥90 mL/min/1.73 m² is stage G1 (normal or high); 60–89 is G2 (mildly decreased); 45–59 is G3a; 30–44 is G3b; 15–29 is G4 (severely decreased); <15 is G5 (kidney failure).
Units: mL/min/1.73 m²
Measured In: 1 test
Category: —

Functional medicine optimaleGFR ≥90 mL/min/1.73 m² is considered normal in the absence of structural kidney damage; persistent values <60 define CKD stage 3 or worse.

What is Estimated Glomerular Filtration Rate (Cystatin C)?

The eGFRcys is calculated from serum cystatin C, age, and sex using the CKD-EPI 2012 cystatin C equation. It estimates the volume of plasma filtered by the glomeruli per unit time, standardised to body surface area, without the confounding influence of muscle mass that limits creatinine-based estimates.

Why is Estimated Glomerular Filtration Rate (Cystatin C) measured?

eGFRcys is a more accurate filtration marker in patients with sarcopaenia, obesity, limb amputation, chronic illness, or extremes of age. It detects earlier declines in kidney function and reclassifies a meaningful proportion of patients compared with creatinine eGFR alone. Combined creatinine–cystatin C equations (eGFRcr-cys) are now recommended by KDIGO when confirmatory testing is needed.

Reference ranges

Standard reference: ≥90 mL/min/1.73 m² is stage G1 (normal or high); 60–89 is G2 (mildly decreased); 45–59 is G3a; 30–44 is G3b; 15–29 is G4 (severely decreased); <15 is G5 (kidney failure).
Functional medicine optimal: eGFR ≥90 mL/min/1.73 m² is considered normal in the absence of structural kidney damage; persistent values <60 define CKD stage 3 or worse.
Units: mL/min/1.73 m²

Reference ranges vary by laboratory and assay platform. Interpret in context of the issuing laboratory's stated range.

Tests that measure Estimated Glomerular Filtration Rate (Cystatin C)

1 test on BiomarkersLabs.com include this biomarker.

BML-KID-011Comprehensive

Cystatin C with Glomerular Filtration Rate, Estimated (eGFR)

Estimated Glomerular Filtration Rate (Cystatin C) reference range in this test: ≥90 mL/min/1.73 m² is stage G1 (normal or high); 60–89 is G2 (mildly decreased); 45–59 is G3a; 30–44 is G3b; 15–29 is G4 (severely decreased); <15 is G5 (kidney failure).

Related clinical conditions

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Frequently measured alongside

Cystatin CCys C2 tests

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