Which tests measure Faecal Elastase-1?

Faecal Elastase-1 is measured in 1 test on BiomarkersLabs.com, including Comprehensive Stool Analysis + Parasitology - 1 Day.

Biomarker Reference · Elastase-1

What does the Faecal Elastase-1 test measure?

Q: Why is Faecal Elastase-1 measured?

Faecal elastase-1 is the non-invasive test of choice for screening exocrine pancreatic insufficiency — seen in chronic pancreatitis, cystic fibrosis, pancreatic cancer, and coeliac disease. Values below 200 µg/g prompt consideration of pancreatic enzyme replacement; below 100 µg/g is diagnostic of severe insufficiency. False-positive (low) results occur with watery diarrhoea due to dilution.

Q: What is the reference range for Faecal Elastase-1?

The standard reference range for Faecal Elastase-1 is >200 µg/g normal pancreatic function; 100–200 µg/g mild to moderate insufficiency; <100 µg/g severe exocrine pancreatic insufficiency.. Reference ranges vary by laboratory and assay platform — interpret in context of the issuing laboratory's stated range.

Faecal Elastase-1 (Elastase-1) is a clinical biomarker used in microbiome-gut assessment. Pancreatic elastase-1 is a protease synthesised by pancreatic acinar cells, secreted into the duodenum, and stable during intestinal transit. It is measured in 1 laboratory test on BiomarkersLabs.com.

Reference Range: >200 µg/g normal pancreatic function; 100–200 µg/g mild to moderate insufficiency; <100 µg/g severe exocrine pancreatic insufficiency.
Units: µg/g
Measured In: 1 test
Category: —

Functional medicine optimal>200 µg/g; values 100–200 µg/g warrant clinical correlation; <100 µg/g indicates severe insufficiency and is an indication for enzyme replacement.

What is Faecal Elastase-1?

Pancreatic elastase-1 is a protease synthesised by pancreatic acinar cells, secreted into the duodenum, and stable during intestinal transit. Its concentration in stool reflects exocrine pancreatic output and is not degraded by pancreatic enzyme replacement therapy, making it a specific marker of endogenous pancreatic function.

Why is Faecal Elastase-1 measured?

Faecal elastase-1 is the non-invasive test of choice for screening exocrine pancreatic insufficiency — seen in chronic pancreatitis, cystic fibrosis, pancreatic cancer, and coeliac disease. Values below 200 µg/g prompt consideration of pancreatic enzyme replacement; below 100 µg/g is diagnostic of severe insufficiency. False-positive (low) results occur with watery diarrhoea due to dilution.

Reference ranges

Standard reference: >200 µg/g normal pancreatic function; 100–200 µg/g mild to moderate insufficiency; <100 µg/g severe exocrine pancreatic insufficiency.
Functional medicine optimal: >200 µg/g; values 100–200 µg/g warrant clinical correlation; <100 µg/g indicates severe insufficiency and is an indication for enzyme replacement.
Units: µg/g

Reference ranges vary by laboratory and assay platform. Interpret in context of the issuing laboratory's stated range.

Tests that measure Faecal Elastase-1

1 test on BiomarkersLabs.com include this biomarker.

BML-MBG-013Comprehensive

Comprehensive Stool Analysis + Parasitology - 1 Day

Faecal Elastase-1 reference range in this test: >200 µg/g normal pancreatic function; 100–200 µg/g mild to moderate insufficiency; <100 µg/g severe exocrine pancreatic insufficiency.

Related clinical conditions

Related Biomarkers

Frequently measured alongside

Commensal Bacterial FloraCommensal Flora1 test Opportunistic and Pathogenic BacteriaOpportunistic Pathogens1 test Yeast and Fungal OrganismsYeast1 test Parasites (Ova, Cysts, Trophozoites)Parasites2 tests Faecal CalprotectinCalprotectin2 tests Secretory Immunoglobulin AsIgA2 tests Faecal pHpH2 tests Short-Chain Fatty Acids (Acetate, Propionate, Butyrate)SCFA4 tests

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