Which tests measure Folate (Serum)?

Folate (Serum) is measured in 1 test on BiomarkersLabs.com, including Vitamin B12 and Folate Panel.

Biomarker Reference · Folate

What does the Folate (Serum) test measure?

Q: Why is Folate (Serum) measured?

Serum folate reflects recent intake and is used alongside B12 in the workup of macrocytic anaemia and suspected deficiency. Serum levels are labile and respond quickly to diet, so a single low value may reflect transient intake rather than depleted stores. Critically, folate must be interpreted with B12, because folate supplementation can correct the anaemia of B12 deficiency while allowing neurological damage to progress unchecked.

Q: What is the reference range for Folate (Serum)?

The standard reference range for Folate (Serum) is >4.0 ng/mL (>9.0 nmol/L) generally adequate; <3.0 ng/mL (<7.0 nmol/L) suggests deficiency # REVIEWER FLAG: Folate reference cut-offs are assay-dependent — reviewer to confirm against Access Medical Laboratories' assay-specific range.. Reference ranges vary by laboratory and assay platform — interpret in context of the issuing laboratory's stated range.

Folate (Serum) (Folate) is a clinical biomarker used in vitamins-minerals assessment. Folate is a water-soluble B vitamin obtained from leafy vegetables, legumes, and fortified foods, absorbed in the proximal small intestine and circulating principally as 5-methyltetrahydrofolate. It is measured in 1 laboratory test on BiomarkersLabs.com.

Reference Range: >4.0 ng/mL (>9.0 nmol/L) generally adequate; <3.0 ng/mL (<7.0 nmol/L) suggests deficiency # REVIEWER FLAG: Folate reference cut-offs are assay-dependent — reviewer to confirm against Access Medical Laboratories' assay-specific range.
Units: ng/mL, nmol/L
Measured In: 1 test
Category: Vitamins & Minerals

Functional medicine optimalLevels comfortably above the deficiency cut-off are adequate; interpreted with B12 rather than as an independent target

What is Folate (Serum)?

Folate is a water-soluble B vitamin obtained from leafy vegetables, legumes, and fortified foods, absorbed in the proximal small intestine and circulating principally as 5-methyltetrahydrofolate. Body stores are modest and can be depleted within weeks of inadequate intake. Folate is essential for one-carbon metabolism, DNA synthesis, and the remethylation of homocysteine to methionine, a step that also requires B12.

Why is Folate (Serum) measured?

Serum folate reflects recent intake and is used alongside B12 in the workup of macrocytic anaemia and suspected deficiency. Serum levels are labile and respond quickly to diet, so a single low value may reflect transient intake rather than depleted stores. Critically, folate must be interpreted with B12, because folate supplementation can correct the anaemia of B12 deficiency while allowing neurological damage to progress unchecked.

Reference ranges

Standard reference: >4.0 ng/mL (>9.0 nmol/L) generally adequate; <3.0 ng/mL (<7.0 nmol/L) suggests deficiency # REVIEWER FLAG: Folate reference cut-offs are assay-dependent — reviewer to confirm against Access Medical Laboratories' assay-specific range.
Functional medicine optimal: Levels comfortably above the deficiency cut-off are adequate; interpreted with B12 rather than as an independent target
Units: ng/mL, nmol/L

Reference ranges vary by laboratory and assay platform. Interpret in context of the issuing laboratory's stated range.

Tests that measure Folate (Serum)

1 test on BiomarkersLabs.com include this biomarker.

BML-VIT-009Comprehensive

Vitamin B12 and Folate Panel

Folate (Serum) reference range in this test: >4.0 ng/mL (>9.0 nmol/L) generally adequate; <3.0 ng/mL (<7.0 nmol/L) suggests deficiency # REVIEWER FLAG: Folate reference cut-offs are assay-dependent — reviewer to confirm against Access Medical Laboratories' assay-specific range.

Related clinical conditions

Related Biomarkers

Frequently measured alongside

Vitamin B12B125 tests

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