What is Neisseria gonorrhoeae nucleic acid?
Neisseria gonorrhoeae is a Gram-negative diplococcus that infects mucosal epithelium of the urethra, endocervix, rectum, pharynx, and conjunctiva. Ascending infection in women causes pelvic inflammatory disease; disseminated gonococcal infection, though uncommon, manifests as arthritis-dermatitis syndrome or, rarely, endocarditis or meningitis. Transcription-mediated amplification detects gonococcal ribosomal RNA with high sensitivity, exceeding that of culture while preserving specificity.