Biomarker Reference · B-vitamin OA
Functional B-Vitamin Markers (B-vitamin OA) is a clinical biomarker used in metabolic-diabetes assessment. Specific organic acids accumulate when B-vitamin-dependent enzymatic steps are under-supported — for example methylmalonate in relation to B12, formiminoglutamate (FIGLU) in relation to folate, and xanthurenate in relation to B6. It is measured in 1 laboratory test on BiomarkersLabs.com.
Specific organic acids accumulate when B-vitamin-dependent enzymatic steps are under-supported — for example methylmalonate in relation to B12, formiminoglutamate (FIGLU) in relation to folate, and xanthurenate in relation to B6. Elevations indicate functional insufficiency at the cellular level.
These functional markers are interpreted as indicators of cellular B-vitamin adequacy, complementing direct serum vitamin measurement. Methylmalonate in particular has recognised validity for B12 status, while other markers are more functional-medicine-oriented. # REVIEWER FLAG: Distinguish validated (e.g. MMA) from exploratory markers.
Reference ranges vary by laboratory and assay platform. Interpret in context of the issuing laboratory's stated range.
1 test on BiomarkersLabs.com include this biomarker.
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