Which tests measure Oestradiol (17-beta-oestradiol)?

Oestradiol (17-beta-oestradiol) is measured in 1 test on BiomarkersLabs.com, including Oestradiol (Estradiol, E2) Test.

Biomarker Reference · E2

What does the Oestradiol (17-beta-oestradiol) test measure?

Q: Why is Oestradiol (17-beta-oestradiol) measured?

Oestradiol measurement is central to assessing ovarian function, characterising the menstrual cycle, and investigating disorders of puberty, amenorrhoea, and the menopausal transition. It is used in fertility evaluation and assisted reproduction to monitor follicular development, and to investigate suspected oestrogen-secreting tumours or feminisation. As with progesterone, interpretation depends heavily on cycle timing, sex, and clinical context, and the assay method matters at low concentrations.

Q: What is the reference range for Oestradiol (17-beta-oestradiol)?

The standard reference range for Oestradiol (17-beta-oestradiol) is Follicular: 20–150 pg/mL; mid-cycle peak: 150–750 pg/mL; luteal: 30–450 pg/mL; postmenopausal: <30 pg/mL # REVIEWER FLAG: Reference ranges are phase-, sex-, and assay-dependent — reviewer to confirm against Quest's assay-specific intervals.. Reference ranges vary by laboratory and assay platform — interpret in context of the issuing laboratory's stated range.

Oestradiol (17-beta-oestradiol) (E2) is a clinical biomarker used in female-hormones assessment. Oestradiol is the most potent endogenous oestrogen, synthesised principally by ovarian granulosa cells from androgen precursors via aromatase, with smaller contributions from peripheral aromatisation in adipose tissue and, in males, the testes. It is measured in 1 laboratory test on BiomarkersLabs.com.

Reference Range: Follicular: 20–150 pg/mL; mid-cycle peak: 150–750 pg/mL; luteal: 30–450 pg/mL; postmenopausal: <30 pg/mL # REVIEWER FLAG: Reference ranges are phase-, sex-, and assay-dependent — reviewer to confirm against Quest's assay-specific intervals.
Units: pg/mL, pmol/L
Measured In: 1 test
Category: Female Hormones

Functional medicine optimalPhase-dependent; interpreted against cycle stage and clinical context rather than a single optimal value

What is Oestradiol (17-beta-oestradiol)?

Oestradiol is the most potent endogenous oestrogen, synthesised principally by ovarian granulosa cells from androgen precursors via aromatase, with smaller contributions from peripheral aromatisation in adipose tissue and, in males, the testes. It circulates largely bound to sex hormone-binding globulin and albumin, with a small free bioactive fraction. Levels fluctuate markedly across the menstrual cycle, peaking just before ovulation, and decline substantially after menopause. Oestradiol drives endometrial proliferation, follicular development, and secondary sexual characteristics.

Why is Oestradiol (17-beta-oestradiol) measured?

Oestradiol measurement is central to assessing ovarian function, characterising the menstrual cycle, and investigating disorders of puberty, amenorrhoea, and the menopausal transition. It is used in fertility evaluation and assisted reproduction to monitor follicular development, and to investigate suspected oestrogen-secreting tumours or feminisation. As with progesterone, interpretation depends heavily on cycle timing, sex, and clinical context, and the assay method matters at low concentrations.

Reference ranges

Standard reference: Follicular: 20–150 pg/mL; mid-cycle peak: 150–750 pg/mL; luteal: 30–450 pg/mL; postmenopausal: <30 pg/mL # REVIEWER FLAG: Reference ranges are phase-, sex-, and assay-dependent — reviewer to confirm against Quest's assay-specific intervals.
Functional medicine optimal: Phase-dependent; interpreted against cycle stage and clinical context rather than a single optimal value
Units: pg/mL, pmol/L

Reference ranges vary by laboratory and assay platform. Interpret in context of the issuing laboratory's stated range.

Tests that measure Oestradiol (17-beta-oestradiol)

1 test on BiomarkersLabs.com include this biomarker.

BML-HRF-002Comprehensive

Oestradiol (Estradiol, E2) Test

Oestradiol (17-beta-oestradiol) reference range in this test: Follicular: 20–150 pg/mL; mid-cycle peak: 150–750 pg/mL; luteal: 30–450 pg/mL; postmenopausal: <30 pg/mL # REVIEWER FLAG: Reference ranges are phase-, sex-, and assay-dependent — reviewer to confirm against Quest's assay-specific intervals.

Related clinical conditions

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