What is the reference range for Anticardiolipin IgM?

The standard reference range for Anticardiolipin IgM is 80 high positive.. Reference ranges vary by laboratory and assay platform — interpret in context of the issuing laboratory's stated range.

Which tests measure Anticardiolipin IgM?

Anticardiolipin IgM is measured in 1 test on BiomarkersLabs.com, including Anticardiolipin Antibodies.

Biomarker Reference · aCL IgM

What does the Anticardiolipin IgM test measure?

Q: Why is Anticardiolipin IgM measured?

IgM aCL is less specific for antiphospholipid syndrome than IgG. Isolated IgM positivity, especially at low titre, is often transient and may follow infection; persistent moderate-to-high IgM can support an APS diagnosis when clinical criteria are met, but the prognostic weight is lower than for IgG.

Anticardiolipin IgM (aCL IgM) is a clinical biomarker used in cardiovascular assessment. IgM anticardiolipin antibodies represent an earlier or transient immune response to phospholipid–protein complexes. It is measured in 1 laboratory test on BiomarkersLabs.com.

Reference Range: <20 MPL U/mL negative; 20–80 low-to-moderate positive; >80 high positive.
Units: MPL U/mL, CU
Measured In: 1 test
Category: Cardiovascular

Functional medicine optimalNegative (<20 MPL U/mL). Persistent moderate-to-high positivity on repeat testing ≥12 weeks apart may contribute to APS classification.

What is Anticardiolipin IgM?

IgM anticardiolipin antibodies represent an earlier or transient immune response to phospholipid–protein complexes. They are more commonly transient and infection-associated than IgG, though persistent moderate-to-high IgM can contribute to APS classification in some patients.

Why is Anticardiolipin IgM measured?

IgM aCL is less specific for antiphospholipid syndrome than IgG. Isolated IgM positivity, especially at low titre, is often transient and may follow infection; persistent moderate-to-high IgM can support an APS diagnosis when clinical criteria are met, but the prognostic weight is lower than for IgG.

Reference ranges

Standard reference: <20 MPL U/mL negative; 20–80 low-to-moderate positive; >80 high positive.
Functional medicine optimal: Negative (<20 MPL U/mL). Persistent moderate-to-high positivity on repeat testing ≥12 weeks apart may contribute to APS classification.
Units: MPL U/mL, CU

Reference ranges vary by laboratory and assay platform. Interpret in context of the issuing laboratory's stated range.

Tests that measure Anticardiolipin IgM

1 test on BiomarkersLabs.com include this biomarker.

BML-CAR-040Comprehensive

Anticardiolipin Antibodies

Anticardiolipin IgM reference range in this test: <20 MPL U/mL negative; 20–80 low-to-moderate positive; >80 high positive.

Related clinical conditions

Related Biomarkers

Frequently measured alongside

Anticardiolipin IgGaCL IgG1 test Anticardiolipin IgAaCL IgA1 test

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