What is the reference range for Anticardiolipin Antibody IgG?

The standard reference range for Anticardiolipin Antibody IgG is Negative or low ( 80. Reference ranges vary by laboratory and assay platform — interpret in context of the issuing laboratory's stated range.

Which tests measure Anticardiolipin Antibody IgG?

Anticardiolipin Antibody IgG is measured in 1 test on BiomarkersLabs.com, including Antiphospholipid Antibody Panel.

Biomarker Reference · aCL IgG

What does the Anticardiolipin Antibody IgG test measure?

Q: Why is Anticardiolipin Antibody IgG measured?

Moderate-to-high titre IgG anticardiolipin, confirmed on repeat testing twelve weeks apart, forms part of the laboratory criteria for antiphospholipid syndrome. The antibody can appear transiently after infection or be seen in autoimmune disease without thrombosis, so clinical context and persistence are essential to interpretation.

Anticardiolipin Antibody IgG (aCL IgG) is a clinical biomarker used in cardiovascular assessment. Anticardiolipin antibodies recognise complexes of cardiolipin — a negatively charged phospholipid — and the plasma protein β2-glycoprotein-I. It is measured in 1 laboratory test on BiomarkersLabs.com.

Reference Range: Negative or low (<20 GPL U/mL); moderate 20–80, high >80
Units: GPL U/mL, CU
Measured In: 1 test
Category: Cardiovascular

Functional medicine optimalNegative; low titres (<20 GPL U/mL) may be transient or clinically insignificant and require correlation and repeat.

What is Anticardiolipin Antibody IgG?

Anticardiolipin antibodies recognise complexes of cardiolipin — a negatively charged phospholipid — and the plasma protein β2-glycoprotein-I. The IgG isotype is measured by enzyme-linked immunosorbent assay, and titre is reported in GPL units (IgG phospholipid units), a semi-quantitative convention standardised to international reference sera. Low-positive titres are common and often transient; moderate-to-high persistent titres correlate better with thrombotic and obstetric risk.

Why is Anticardiolipin Antibody IgG measured?

Moderate-to-high titre IgG anticardiolipin, confirmed on repeat testing twelve weeks apart, forms part of the laboratory criteria for antiphospholipid syndrome. The antibody can appear transiently after infection or be seen in autoimmune disease without thrombosis, so clinical context and persistence are essential to interpretation.

Reference ranges

Standard reference: Negative or low (<20 GPL U/mL); moderate 20–80, high >80
Functional medicine optimal: Negative; low titres (<20 GPL U/mL) may be transient or clinically insignificant and require correlation and repeat.
Units: GPL U/mL, CU

Reference ranges vary by laboratory and assay platform. Interpret in context of the issuing laboratory's stated range.

Tests that measure Anticardiolipin Antibody IgG

1 test on BiomarkersLabs.com include this biomarker.

BML-CAR-041Comprehensive

Antiphospholipid Antibody Panel

Anticardiolipin Antibody IgG reference range in this test: Negative or low (<20 GPL U/mL); moderate 20–80, high >80

Related clinical conditions

Related Biomarkers

Frequently measured alongside

Lupus AnticoagulantLA1 test Anticardiolipin Antibody IgMaCL IgM1 test Anti-β2-Glycoprotein-I Antibody IgGanti-β2GPI IgG1 test Anti-β2-Glycoprotein-I Antibody IgManti-β2GPI IgM1 test

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