What is the reference range for Pancreatic Elastase-1?

The standard reference range for Pancreatic Elastase-1 is >200 µg/g normal; 100–200 µg/g mild to moderate insufficiency; <100 µg/g severe exocrine insufficiency.. Reference ranges vary by laboratory and assay platform — interpret in context of the issuing laboratory's stated range.

Which tests measure Pancreatic Elastase-1?

Pancreatic Elastase-1 is measured in 1 test on BiomarkersLabs.com, including GI Effects Comprehensive Profile – 1 Day (Stool).

Biomarker Reference · PE-1

What does the Pancreatic Elastase-1 test measure?

Q: Which tests measure Pancreatic Elastase-1?

Pancreatic Elastase-1 is measured in 1 test on BiomarkersLabs.com, including GI Effects Comprehensive Profile – 1 Day (Stool).

Pancreatic Elastase-1 (PE-1) is a clinical biomarker used in gastrointestinal assessment. Pancreatic elastase-1 is a proteolytic enzyme synthesised by the pancreatic acinar cells and secreted into the duodenum. It is measured in 1 laboratory test on BiomarkersLabs.com.

Reference Range: >200 µg/g normal; 100–200 µg/g mild to moderate insufficiency; <100 µg/g severe exocrine insufficiency.
Units: µg/g
Measured In: 1 test
Category: Gastrointestinal

Functional medicine optimal>200 µg/g; values below this threshold warrant further pancreatic investigation and consideration of enzyme supplementation.

What is Pancreatic Elastase-1?

Pancreatic elastase-1 is a proteolytic enzyme synthesised by the pancreatic acinar cells and secreted into the duodenum. Because it is not degraded during intestinal transit and its faecal concentration correlates with pancreatic output, it serves as a non-invasive marker of exocrine pancreatic function.

Why is Pancreatic Elastase-1 measured?

Low faecal elastase-1 indicates exocrine pancreatic insufficiency, which may be secondary to chronic pancreatitis, cystic fibrosis, pancreatic cancer, or severe coeliac disease. It is used to guide pancreatic enzyme replacement therapy and to differentiate malabsorption aetiologies.

Reference ranges

Standard reference: >200 µg/g normal; 100–200 µg/g mild to moderate insufficiency; <100 µg/g severe exocrine insufficiency.
Functional medicine optimal: >200 µg/g; values below this threshold warrant further pancreatic investigation and consideration of enzyme supplementation.
Units: µg/g

Reference ranges vary by laboratory and assay platform. Interpret in context of the issuing laboratory's stated range.

Tests that measure Pancreatic Elastase-1

1 test on BiomarkersLabs.com include this biomarker.

BML-GAS-045Comprehensive

GI Effects Comprehensive Profile – 1 Day (Stool)

Pancreatic Elastase-1 reference range in this test: >200 µg/g normal; 100–200 µg/g mild to moderate insufficiency; <100 µg/g severe exocrine insufficiency.

Related clinical conditions

Related Biomarkers

Frequently measured alongside

Faecal CalprotectinCalprotectin2 tests Secretory Immunoglobulin AsIgA2 tests Beta-Glucuronidaseβ-Gluc2 tests Short-Chain Fatty Acids (Acetate, Propionate, Butyrate)SCFA4 tests Faecal Fat (Steatocrit or Qualitative)Steatocrit1 test Faecal Occult BloodFOB1 test Microbial diversity (Shannon index)Shannon H'2 tests Pathogen PCR Detection PanelPathogen PCR1 test

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