What is Food-Specific Immunoglobulin G?
IgG is the most abundant serum immunoglobulin and is generated in response to chronic or repeated antigen exposure. In the context of food, IgG antibodies reflect exposure and immunological memory but do not necessarily indicate adverse reactivity — they are a normal consequence of eating and can be elevated to commonly consumed foods in healthy individuals. The role of IgG in non-IgE-mediated food reactions is debated; mainstream allergy societies do not endorse IgG testing for food intolerance, citing lack of diagnostic specificity.