Biomarker Reference · Free T
Testosterone, Free (Free T) is a clinical biomarker used in male-hormones assessment. Free testosterone is the small unbound fraction not attached to SHBG or albumin and is considered the immediately bioavailable, biologically active portion. It is measured in 2 laboratory tests on BiomarkersLabs.com.
Free testosterone is the small unbound fraction not attached to SHBG or albumin and is considered the immediately bioavailable, biologically active portion. In this panel it is typically calculated from total testosterone, SHBG, and albumin rather than measured directly, since direct analogue immunoassays for free testosterone are regarded as unreliable.
Free testosterone clarifies androgen status when total testosterone is equivocal or SHBG is altered by obesity, thyroid disease, hepatic disease, ageing, or hormonal therapy. It is particularly useful in diagnosing hypogonadism where total testosterone sits near the lower reference limit, and in assessing androgen excess in women.
Reference ranges vary by laboratory and assay platform. Interpret in context of the issuing laboratory's stated range.
2 tests on BiomarkersLabs.com include this biomarker.
Testosterone, Free reference range in this test: Adult men ~50–210 pg/mL; method-dependent # REVIEWER FLAG: Free testosterone ranges vary by method (equilibrium dialysis vs calculated) — reviewer to confirm LabCorp method and range.
Testosterone, Free reference range in this test: Adult men ~50–210 pg/mL; method-dependent # REVIEWER FLAG: Calculated free testosterone depends on the equation and albumin assumptions — reviewer to confirm Access Medical Laboratories method and range.
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