What does the Transforming Growth Factor Beta 1 Gene Variant test measure?

Why is Transforming Growth Factor Beta 1 Gene Variant measured?

TGF-β1 variant status contributes to understanding an individual's susceptibility to fibrosis — in the lung, liver, and kidney — and to certain autoimmune conditions. High-secretor genotypes may predispose to excessive tissue remodelling and poorer outcomes in chronic inflammation, though clinical translation remains an area of active investigation.

Reference ranges

Standard reference

Wild-type, heterozygous variant, or homozygous variant reported.

Functional medicine optimal

Not applicable; genotype interpretation is context-dependent and not a standalone diagnostic or therapeutic marker.

Units

genotype

Reference ranges vary by laboratory and assay platform. Interpret in context of the issuing laboratory's stated range.