Which tests measure Total Serum Immunoglobulin E?

Total Serum Immunoglobulin E is measured in 3 tests on BiomarkersLabs.com, including 184 IgG Food Sensitivity & 50 Expanded IgE Combo Panel, Allergy Mold Panel, Complete, Allergy-Mold Profile plus IgE.

Biomarker Reference · Total IgE

What does the Total Serum Immunoglobulin E test measure?

Q: What is the reference range for Total Serum Immunoglobulin E?

The standard reference range for Total Serum Immunoglobulin E is Age-dependent; adults typically <100–150 kU/L, though reference limits vary by laboratory and population.. Reference ranges vary by laboratory and assay platform — interpret in context of the issuing laboratory's stated range.

Total Serum Immunoglobulin E (Total IgE) is a clinical biomarker used in environmental-mould assessment. Total IgE represents the sum of all circulating IgE antibodies, both specific and non-specific. It is measured in 3 laboratory tests on BiomarkersLabs.com.

Reference Range: Age-dependent; adults typically <100–150 kU/L, though reference limits vary by laboratory and population.
Units: kU/L, IU/mL
Measured In: 3 tests
Category: —

Functional medicine optimalLower levels (<50 kU/L in adults) are associated with reduced atopic disease burden. Moderate elevations (150–500 kU/L) suggest significant atopy; very high values (>1000 kU/L) raise suspicion for ABPA or parasitic infection.

What is Total Serum Immunoglobulin E?

Total IgE represents the sum of all circulating IgE antibodies, both specific and non-specific. It is synthesised by B cells in response to allergen exposure, parasitic infection, and certain immunological disorders. Total IgE provides context for interpreting specific IgE results and is a biomarker of atopic status and allergic disease burden.

Why is Total Serum Immunoglobulin E measured?

Markedly elevated total IgE (>1000 kU/L) in the presence of Aspergillus-specific IgE, eosinophilia, and pulmonary infiltrates suggests ABPA. Moderate elevations are common in polysensitised atopic patients and add little diagnostic value in isolation, but serial monitoring can track disease activity in ABPA or guide omalizumab dosing.

Reference ranges

Standard reference: Age-dependent; adults typically <100–150 kU/L, though reference limits vary by laboratory and population.
Functional medicine optimal: Lower levels (<50 kU/L in adults) are associated with reduced atopic disease burden. Moderate elevations (150–500 kU/L) suggest significant atopy; very high values (>1000 kU/L) raise suspicion for ABPA or parasitic infection.
Units: kU/L, IU/mL

Reference ranges vary by laboratory and assay platform. Interpret in context of the issuing laboratory's stated range.

Tests that measure Total Serum Immunoglobulin E

3 tests on BiomarkersLabs.com include this biomarker.

BML-FSA-013Comprehensive

184 IgG Food Sensitivity & 50 Expanded IgE Combo Panel

Total Serum Immunoglobulin E reference range in this test: Age-dependent; adult reference approximately <100–150 kU/L.

BML-ENV-003Comprehensive

Allergy Mold Panel, Complete

Total Serum Immunoglobulin E reference range in this test: Age-dependent; adults typically <100–150 kU/L, though reference limits vary by laboratory and population.

BML-ENV-004Comprehensive

Allergy-Mold Profile plus IgE

Total Serum Immunoglobulin E reference range in this test: Age-dependent; adults typically <100–150 kU/L, though reference limits vary.

Related clinical conditions

Related Biomarkers

Frequently measured alongside

Alternaria alternata IgEAlt a IgE5 tests Aspergillus fumigatus IgEAsp f IgE6 tests Cladosporium herbarum IgECla h IgE5 tests Penicillium notatum-specific IgEPenicillium IgE2 tests Food-Specific Immunoglobulin GIgG12 tests Food-Specific Immunoglobulin E AntibodiesIgE2 tests Candida albicans-specific IgECandida IgE2 tests Mucor racemosus IgEMuc r IgE3 tests

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