What is the reference range for Plasma Aldosterone Concentration?

The standard reference range for Plasma Aldosterone Concentration is Typically 2–30 ng/dL (55–830 pmol/L) upright, lower when supine; method- and posture-dependent.. Reference ranges vary by laboratory and assay platform — interpret in context of the issuing laboratory's stated range.

Which tests measure Plasma Aldosterone Concentration?

Plasma Aldosterone Concentration is measured in 1 test on BiomarkersLabs.com, including Aldosterone/Plasma Renin Activity Ratio, LC/MS/MS.

Biomarker Reference · PAC

What does the Plasma Aldosterone Concentration test measure?

Plasma Aldosterone Concentration (PAC) is a clinical biomarker used in adrenal-stress assessment. Aldosterone is a mineralocorticoid synthesised in the zona glomerulosa of the adrenal cortex under the control of the renin–angiotensin system, serum potassium, and adrenocorticotropic hormone. It is measured in 1 laboratory test on BiomarkersLabs.com.

Reference Range: Typically 2–30 ng/dL (55–830 pmol/L) upright, lower when supine; method- and posture-dependent.
Units: ng/dL, pmol/L
Measured In: 1 test
Category: Adrenal

Functional medicine optimalOptimal ranges are context-specific and defined by the ratio rather than aldosterone alone; interpretation depends on posture, sodium loading, and concurrent renin.

What is Plasma Aldosterone Concentration?

Aldosterone is a mineralocorticoid synthesised in the zona glomerulosa of the adrenal cortex under the control of the renin–angiotensin system, serum potassium, and adrenocorticotropic hormone. It regulates sodium reabsorption and potassium excretion in the distal nephron, thereby controlling blood volume and pressure. Secretion varies markedly with posture, sodium balance, and time of day, so sampling conditions must be standardised.

Why is Plasma Aldosterone Concentration measured?

Plasma aldosterone concentration is the numerator of the aldosterone/renin ratio and the primary measure of mineralocorticoid output. Isolated aldosterone values are difficult to interpret without knowing renin status, because aldosterone should be suppressed when renin is low and stimulated when renin is high; inappropriate elevation in the setting of suppressed renin defines primary aldosteronism.

Reference ranges

Standard reference: Typically 2–30 ng/dL (55–830 pmol/L) upright, lower when supine; method- and posture-dependent.
Functional medicine optimal: Optimal ranges are context-specific and defined by the ratio rather than aldosterone alone; interpretation depends on posture, sodium loading, and concurrent renin.
Units: ng/dL, pmol/L

Reference ranges vary by laboratory and assay platform. Interpret in context of the issuing laboratory's stated range.

Tests that measure Plasma Aldosterone Concentration

1 test on BiomarkersLabs.com include this biomarker.

BML-ADR-024Comprehensive

Aldosterone/Plasma Renin Activity Ratio, LC/MS/MS

Plasma Aldosterone Concentration reference range in this test: Typically 2–30 ng/dL (55–830 pmol/L) upright, lower when supine; method- and posture-dependent.

Related clinical conditions

Related Biomarkers

Frequently measured alongside

Plasma Renin ActivityPRA1 test Aldosterone/Plasma Renin Activity RatioARR1 test

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