Which tests measure Aldosterone/Plasma Renin Activity Ratio?

Aldosterone/Plasma Renin Activity Ratio is measured in 1 test on BiomarkersLabs.com, including Aldosterone/Plasma Renin Activity Ratio, LC/MS/MS.

Biomarker Reference · ARR

What does the Aldosterone/Plasma Renin Activity Ratio test measure?

Q: What is the reference range for Aldosterone/Plasma Renin Activity Ratio?

The standard reference range for Aldosterone/Plasma Renin Activity Ratio is ARR >20–30 (units ng/dL per ng/mL/h) is typically the threshold for further evaluation; cut-off varies by assay and guideline.. Reference ranges vary by laboratory and assay platform — interpret in context of the issuing laboratory's stated range.

Aldosterone/Plasma Renin Activity Ratio (ARR) is a clinical biomarker used in adrenal-stress assessment. The ratio is a derived marker that expresses aldosterone output relative to renin drive. It is measured in 1 laboratory test on BiomarkersLabs.com.

Reference Range: ARR >20–30 (units ng/dL per ng/mL/h) is typically the threshold for further evaluation; cut-off varies by assay and guideline.
Units: (ng/dL)/(ng/mL/h), dimensionless
Measured In: 1 test
Category: Adrenal

Functional medicine optimalRatios below the screening threshold effectively exclude primary aldosteronism when sampled under appropriate conditions; borderline values require careful clinical correlation and often repeat or confirmatory testing.

What is Aldosterone/Plasma Renin Activity Ratio?

The ratio is a derived marker that expresses aldosterone output relative to renin drive. Because aldosterone secretion should track with renin, an inappropriately high ratio — aldosterone that is not suppressed despite low renin — suggests autonomous aldosterone production independent of the renin–angiotensin axis.

Why is Aldosterone/Plasma Renin Activity Ratio measured?

The aldosterone/renin ratio is the best initial screening test for primary aldosteronism in patients with hypertension and hypokalaemia or resistant hypertension. A high ratio prompts confirmatory testing (saline suppression, oral sodium loading, or captopril challenge) and, if confirmed, imaging and possibly adrenal vein sampling to distinguish unilateral from bilateral disease.

Reference ranges

Standard reference: ARR >20–30 (units ng/dL per ng/mL/h) is typically the threshold for further evaluation; cut-off varies by assay and guideline.
Functional medicine optimal: Ratios below the screening threshold effectively exclude primary aldosteronism when sampled under appropriate conditions; borderline values require careful clinical correlation and often repeat or confirmatory testing.
Units: (ng/dL)/(ng/mL/h), dimensionless

Reference ranges vary by laboratory and assay platform. Interpret in context of the issuing laboratory's stated range.

Tests that measure Aldosterone/Plasma Renin Activity Ratio

1 test on BiomarkersLabs.com include this biomarker.

BML-ADR-024Comprehensive

Aldosterone/Plasma Renin Activity Ratio, LC/MS/MS

Aldosterone/Plasma Renin Activity Ratio reference range in this test: ARR >20–30 (units ng/dL per ng/mL/h) is typically the threshold for further evaluation; cut-off varies by assay and guideline.

Related clinical conditions

Related Biomarkers

Frequently measured alongside

Plasma Aldosterone ConcentrationPAC1 test Plasma Renin ActivityPRA1 test

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