What is Androgen Metabolites (DHEA-S, Testosterone, 5a-DHT metabolites, Androsterone, Etiocholanolone)?
DHEA-S is the principal adrenal androgen precursor, while downstream androgens including testosterone are metabolised via 5-alpha and 5-beta pathways to androsterone and etiocholanolone, excreted in urine. The relative activity of 5-alpha reductase, inferred from metabolite ratios, influences potent androgen exposure at tissue level. Dried urine captures these metabolites to profile androgen production and metabolism.