Biomarker Reference · β2GPI IgA
Beta-2-Glycoprotein I Antibody, IgA (β2GPI IgA) is a clinical biomarker used in autoimmune-inflammation assessment. The IgA isotype of β2GPI antibodies is less well characterised than IgG and is not a formal classification criterion under the revised Sapporo criteria. It is measured in 1 laboratory test on BiomarkersLabs.com.
The IgA isotype of β2GPI antibodies is less well characterised than IgG and is not a formal classification criterion under the revised Sapporo criteria. Nevertheless, a subset of patients with clinical features of antiphospholipid syndrome test positive only for IgA, particularly in the context of systemic lupus erythematosus or catastrophic APS.
Inclusion of β2GPI IgA testing may identify patients who are 'seronegative' by classic criteria but who carry antiphospholipid antibody–mediated risk. Its independent predictive value remains debated, and it is not universally measured in all laboratories.
Reference ranges vary by laboratory and assay platform. Interpret in context of the issuing laboratory's stated range.
1 test on BiomarkersLabs.com include this biomarker.
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