What is the reference range for Beta-2-Glycoprotein I Antibody, IgM?

The standard reference range for Beta-2-Glycoprotein I Antibody, IgM is 80 U/mL positive (assay-dependent).. Reference ranges vary by laboratory and assay platform — interpret in context of the issuing laboratory's stated range.

Which tests measure Beta-2-Glycoprotein I Antibody, IgM?

Beta-2-Glycoprotein I Antibody, IgM is measured in 1 test on BiomarkersLabs.com, including Beta-2-Glycoprotein I Antibodies (IgG, IgA, IgM).

Biomarker Reference · β2GPI IgM

What does the Beta-2-Glycoprotein I Antibody, IgM test measure?

Q: Why is Beta-2-Glycoprotein I Antibody, IgM measured?

β2GPI IgM is less consistently associated with thrombotic events than IgG. Isolated IgM positivity, especially at low titre, often reflects a transient response and must be confirmed at 12 weeks before attributing clinical significance.

Beta-2-Glycoprotein I Antibody, IgM (β2GPI IgM) is a clinical biomarker used in autoimmune-inflammation assessment. IgM antibodies to β2GPI occur transiently after infections or may appear alongside IgG in autoimmune contexts. It is measured in 1 laboratory test on BiomarkersLabs.com.

Reference Range: <20 U/mL negative; 20–80 U/mL indeterminate; >80 U/mL positive (assay-dependent).
Units: U/mL, MPL U/mL
Measured In: 1 test
Category: Autoimmune

Functional medicine optimalNegative (<20 U/mL).

What is Beta-2-Glycoprotein I Antibody, IgM?

IgM antibodies to β2GPI occur transiently after infections or may appear alongside IgG in autoimmune contexts. IgM is larger and pentameric, leading to different complement-activating properties compared with IgG, and is more likely to be a false-positive or transient finding.

Why is Beta-2-Glycoprotein I Antibody, IgM measured?

β2GPI IgM is less consistently associated with thrombotic events than IgG. Isolated IgM positivity, especially at low titre, often reflects a transient response and must be confirmed at 12 weeks before attributing clinical significance.

Reference ranges

Standard reference: <20 U/mL negative; 20–80 U/mL indeterminate; >80 U/mL positive (assay-dependent).
Functional medicine optimal: Negative (<20 U/mL).
Units: U/mL, MPL U/mL

Reference ranges vary by laboratory and assay platform. Interpret in context of the issuing laboratory's stated range.

Tests that measure Beta-2-Glycoprotein I Antibody, IgM

1 test on BiomarkersLabs.com include this biomarker.

BML-AUT-016Comprehensive

Beta-2-Glycoprotein I Antibodies (IgG, IgA, IgM)

Beta-2-Glycoprotein I Antibody, IgM reference range in this test: <20 U/mL negative; 20–80 U/mL indeterminate; >80 U/mL positive (assay-dependent).

Related clinical conditions

Related Biomarkers

Frequently measured alongside

Beta-2-Glycoprotein I Antibody, IgGβ2GPI IgG1 test Beta-2-Glycoprotein I Antibody, IgAβ2GPI IgA1 test

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