Biomarker Reference · Candida IgA
Candida IgA Antibody (Candida IgA) is a clinical biomarker used in autoimmune-inflammation assessment. IgA is the predominant immunoglobulin at mucosal surfaces and in secretions, where it binds and neutralises antigens without triggering inflammation. It is measured in 3 laboratory tests on BiomarkersLabs.com.
IgA is the predominant immunoglobulin at mucosal surfaces and in secretions, where it binds and neutralises antigens without triggering inflammation. Elevated secretory and serum IgA to Candida can reflect active mucosal infection, recurrent vulvovaginal or oropharyngeal candidiasis, or chronic gut colonisation with immune activation. IgA responses are shorter-lived than IgG and more closely track active or recent mucosal challenge.
Elevated Candida IgA is used by some practitioners as a marker of mucosal candidiasis, particularly in the gastrointestinal tract. Chronic mucosal inflammation, disrupted barrier function, and immune dysregulation may all drive IgA production. However, the clinical validity of IgA serology for diagnosing 'intestinal candida overgrowth' outside overt thrush or oesophagitis is debated, and results must be contextualised with clinical symptoms and direct mucosal assessment where feasible.
Reference ranges vary by laboratory and assay platform. Interpret in context of the issuing laboratory's stated range.
3 tests on BiomarkersLabs.com include this biomarker.
Candida IgA Antibody reference range in this test: Method-specific; typically <1.0 index value negative, ≥1.0 positive or equivocal.
Candida IgA Antibody reference range in this test: Negative <91 units; equivocal 91–110 units; positive >110 units (assay-dependent)
Candida IgA Antibody reference range in this test: Laboratory-specific index; typically <0.9 negative, 0.9–1.1 equivocal, >1.1 positive.
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