What does the Cardiovascular Genetic Risk Score test measure?

Why is Cardiovascular Genetic Risk Score measured?

The composite score helps practitioners identify patients who carry both a high genetic cardiovascular burden (elevated Lp(a)) and a potentially modifiable metabolic liability (MTHFR variants associated with hyperhomocysteinaemia). It supports personalised risk stratification and nutrient intervention but is not a stand-alone diagnostic and must be integrated with standard lipid panels, homocysteine measurement, and established cardiovascular risk calculators. The clinical validity of combining these markers into a single score is proprietary to the testing laboratory and has not been independently validated in outcomes trials.

Reference ranges

Standard reference

Laboratory-specific composite interpretation combining Lp(a) concentration and MTHFR genotype.

Functional medicine optimal

Laboratory-specific; lower scores reflect lower genetic cardiovascular liability and better folate-metabolism capacity.

Units

composite score

Reference ranges vary by laboratory and assay platform. Interpret in context of the issuing laboratory's stated range.