What is the reference range for Cortisol (Midday Sample)?

The standard reference range for Cortisol (Midday Sample) is Typically 4–10 nmol/L or approximately 1.5–3.6 ng/mL in saliva at midday.. Reference ranges vary by laboratory and assay platform — interpret in context of the issuing laboratory's stated range.

Which tests measure Cortisol (Midday Sample)?

Cortisol (Midday Sample) is measured in 1 test on BiomarkersLabs.com, including Saliva 4-Point Cortisol (Diurnal Profile).

Biomarker Reference · Cortisol Noon

What does the Cortisol (Midday Sample) test measure?

Cortisol (Midday Sample) (Cortisol Noon) is a clinical biomarker used in adrenal-stress assessment. Following the morning peak, cortisol declines throughout the day. It is measured in 1 laboratory test on BiomarkersLabs.com.

Reference Range: Typically 4–10 nmol/L or approximately 1.5–3.6 ng/mL in saliva at midday.
Units: nmol/L, ng/mL
Measured In: 1 test
Category: Adrenal

Functional medicine optimalFunctional zones may emphasise a proportional decline from the morning value rather than an absolute threshold.

What is Cortisol (Midday Sample)?

Following the morning peak, cortisol declines throughout the day. The noon sample captures the mid-morning descent, reflecting the transition from peak activity to the afternoon nadir.

Why is Cortisol (Midday Sample) measured?

An elevated midday cortisol relative to the morning value may suggest a flattened rhythm, while a steep drop is consistent with healthy HPA dynamics. The noon point helps define the slope and detect rhythm disruption.

Reference ranges

Standard reference: Typically 4–10 nmol/L or approximately 1.5–3.6 ng/mL in saliva at midday.
Functional medicine optimal: Functional zones may emphasise a proportional decline from the morning value rather than an absolute threshold.
Units: nmol/L, ng/mL

Reference ranges vary by laboratory and assay platform. Interpret in context of the issuing laboratory's stated range.

Tests that measure Cortisol (Midday Sample)

1 test on BiomarkersLabs.com include this biomarker.

BML-ADR-007Comprehensive

Saliva 4-Point Cortisol (Diurnal Profile)

Cortisol (Midday Sample) reference range in this test: Typically 4–10 nmol/L or approximately 1.5–3.6 ng/mL in saliva at midday.

Related clinical conditions

Related Biomarkers

Frequently measured alongside

Serum Cortisol (Waking)Cortisol-0h2 tests Cortisol (evening)Cortisol-PM5 tests Serum Cortisol (Bedtime)Cortisol-Night2 tests Cortisol Diurnal SlopeDiurnal Slope1 test

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