What is Ferritin?
Ferritin is an intracellular iron storage protein composed of 24 heavy and light chain subunits forming a hollow nanocage capable of storing up to 4,500 iron atoms per molecule. A small fraction of intracellular ferritin is glycosylated and secreted into the circulation — serum ferritin concentrations reflect the total body iron store under stable conditions. Ferritin is also an acute phase reactant, rising proportionally with systemic inflammation independent of iron status — a critical interpretive caveat.