What does the Glycine test measure?

Why is Glycine measured?

Urinary glycine patterns are used in functional assessments of methylation, detoxification capacity, and neuroprotection. Elevated glycine may be seen in rare inborn errors of metabolism (non-ketotic hyperglycinaemia), while low levels are proposed to correlate with sleep disturbance or impaired NMDA receptor modulation, though evidence is limited.

Reference ranges

Standard reference

Laboratory-specific functional range; Sanesco reports normalised to creatinine and scored relative to proprietary reference population.

Functional medicine optimal

Functional ranges are proprietary to Sanesco and not standardised across laboratories or against clinical diagnostic criteria.

Units

ng/mg creatinine, µg/g creatinine

Reference ranges vary by laboratory and assay platform. Interpret in context of the issuing laboratory's stated range.