What is the reference range for Glutathione S-Transferase Mu 1 Deletion?

The standard reference range for Glutathione S-Transferase Mu 1 Deletion is Present (functional allele) or Null (homozygous deletion). Reference ranges vary by laboratory and assay platform — interpret in context of the issuing laboratory's stated range.

Which tests measure Glutathione S-Transferase Mu 1 Deletion?

Glutathione S-Transferase Mu 1 Deletion is measured in 1 test on BiomarkersLabs.com, including Add-On MethylDetox Profile.

Biomarker Reference · GSTM1

What does the Glutathione S-Transferase Mu 1 Deletion test measure?

Glutathione S-Transferase Mu 1 Deletion (GSTM1) is a clinical biomarker used in comprehensive-panels assessment. GSTM1 is a phase-II detoxification enzyme that conjugates glutathione to electrophilic xenobiotics and products of oxidative stress, facilitating their excretion. It is measured in 1 laboratory test on BiomarkersLabs.com.

Reference Range: Present (functional allele) or Null (homozygous deletion)
Units: genotype
Measured In: 1 test
Category: —

Functional medicine optimalNot applicable (categorical genotype). Presence of the functional allele is considered favourable for xenobiotic clearance.

What is Glutathione S-Transferase Mu 1 Deletion?

GSTM1 is a phase-II detoxification enzyme that conjugates glutathione to electrophilic xenobiotics and products of oxidative stress, facilitating their excretion. A homozygous deletion polymorphism results in complete absence of GSTM1 enzyme; the null genotype is present in roughly half of many populations.

Why is Glutathione S-Transferase Mu 1 Deletion measured?

The GSTM1-null genotype has been associated in epidemiological studies with modestly increased risk of certain cancers (bladder, lung) and adverse responses to environmental toxins, smoking, and some chemotherapeutic agents. It does not cause disease in isolation and is best viewed as a susceptibility modifier. In functional and integrative medicine it informs discussions of detoxification capacity and may guide environmental-exposure counselling, though evidence for genotype-directed interventions is limited.

Reference ranges

Standard reference: Present (functional allele) or Null (homozygous deletion)
Functional medicine optimal: Not applicable (categorical genotype). Presence of the functional allele is considered favourable for xenobiotic clearance.
Units: genotype

Reference ranges vary by laboratory and assay platform. Interpret in context of the issuing laboratory's stated range.

Tests that measure Glutathione S-Transferase Mu 1 Deletion

1 test on BiomarkersLabs.com include this biomarker.

BML-CHP-016Comprehensive

Add-On MethylDetox Profile

Glutathione S-Transferase Mu 1 Deletion reference range in this test: Present (functional allele) or Null (homozygous deletion)

Related clinical conditions

Related Biomarkers

Frequently measured alongside

Methylenetetrahydrofolate Reductase C677T PolymorphismMTHFR C677T3 tests Methylenetetrahydrofolate Reductase A1298C PolymorphismMTHFR A1298C3 tests Catechol-O-Methyltransferase V158M PolymorphismCOMT V158M2 tests Glutathione S-Transferase Theta 1 DeletionGSTT11 test Superoxide Dismutase 2 Ala16Val VariantSOD2 A16V1 test

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