What does the Norepinephrine (Noradrenaline), Urine test measure?

Why is Norepinephrine (Noradrenaline), Urine measured?

In Sanesco's framework, urinary norepinephrine is assessed alongside epinephrine as a marker of sympathoadrenal output and adrenergic tone, relevant to chronic stress evaluation, autonomic nervous system characterisation, and adrenal-sympathetic depletion patterns. Low norepinephrine alongside low dopamine in the context of fatigue and motivational impairment is interpreted as catecholamine precursor depletion. Elevated norepinephrine — particularly when chronic — is associated with sustained sympathetic activation and is addressed through adrenal support, stress reduction, and precursor balance.

Reference ranges

Standard reference

# REVIEWER FLAG: Confirm Sanesco reference range for urinary norepinephrine.

Functional medicine optimal

# REVIEWER FLAG: Confirm Sanesco optimal range designation.

Units

µg/g creatinine

Reference ranges vary by laboratory and assay platform. Interpret in context of the issuing laboratory's stated range.