Which tests measure Pancreatic Elastase-1?

Pancreatic Elastase-1 is measured in 1 test on BiomarkersLabs.com, including GI Effects Comprehensive Profile – 3 Day (Stool).

Biomarker Reference · PE-1

What does the Pancreatic Elastase-1 test measure?

Q: What is the reference range for Pancreatic Elastase-1?

The standard reference range for Pancreatic Elastase-1 is >200 µg/g normal; 100–200 µg/g moderate insufficiency; <100 µg/g severe exocrine pancreatic insufficiency # REVIEWER FLAG: Confirm Genova cut-offs.. Reference ranges vary by laboratory and assay platform — interpret in context of the issuing laboratory's stated range.

Pancreatic Elastase-1 (PE-1) is a clinical biomarker used in gastrointestinal assessment. Pancreatic elastase-1 is a protease secreted by the exocrine pancreas that remains stable through intestinal transit and is concentrated in stool, making faecal levels a reliable indirect marker of pancreatic exocrine output. It is measured in 1 laboratory test on BiomarkersLabs.com.

Reference Range: >200 µg/g normal; 100–200 µg/g moderate insufficiency; <100 µg/g severe exocrine pancreatic insufficiency # REVIEWER FLAG: Confirm Genova cut-offs.
Units: µg/g
Measured In: 1 test
Category: Gastrointestinal

Functional medicine optimal>200 µg/g # REVIEWER FLAG: Confirm.

What is Pancreatic Elastase-1?

Pancreatic elastase-1 is a protease secreted by the exocrine pancreas that remains stable through intestinal transit and is concentrated in stool, making faecal levels a reliable indirect marker of pancreatic exocrine output. It is not degraded en route and correlates with overall enzyme secretion.

Why is Pancreatic Elastase-1 measured?

Faecal elastase-1 is the principal stool marker of exocrine pancreatic insufficiency, with low levels supporting impaired enzyme secretion as a cause of maldigestion, steatorrhoea, and nutrient malabsorption. It helps distinguish pancreatic from non-pancreatic causes of digestive symptoms.

Reference ranges

Standard reference: >200 µg/g normal; 100–200 µg/g moderate insufficiency; <100 µg/g severe exocrine pancreatic insufficiency # REVIEWER FLAG: Confirm Genova cut-offs.
Functional medicine optimal: >200 µg/g # REVIEWER FLAG: Confirm.
Units: µg/g

Reference ranges vary by laboratory and assay platform. Interpret in context of the issuing laboratory's stated range.

Tests that measure Pancreatic Elastase-1

1 test on BiomarkersLabs.com include this biomarker.

BML-GAS-044Comprehensive

GI Effects Comprehensive Profile – 3 Day (Stool)

Pancreatic Elastase-1 reference range in this test: >200 µg/g normal; 100–200 µg/g moderate insufficiency; <100 µg/g severe exocrine pancreatic insufficiency # REVIEWER FLAG: Confirm Genova cut-offs.

Related clinical conditions

Related Biomarkers

Frequently measured alongside

Faecal CalprotectinCalprotectin1 test Faecal Secretory IgAsIgA1 test Short-Chain Fatty Acids (Acetate, Propionate, Butyrate)SCFA4 tests Beta-Glucuronidaseβ-Gluc2 tests Commensal Bacteria Abundance (PCR panel)Commensals1 test Pathogenic Bacteria, Parasites & Yeast ScreenPathogens1 test

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