What is Faecal Secretory IgA?
Secretory IgA is the principal mucosal antibody, secreted across the gut epithelium to bind pathogens and antigens at the mucosal surface. Faecal levels are taken to reflect mucosal humoral immune activity.
Biomarker Reference · sIgA
Faecal Secretory IgA (sIgA) is a clinical biomarker used in gastrointestinal assessment. Secretory IgA is the principal mucosal antibody, secreted across the gut epithelium to bind pathogens and antigens at the mucosal surface. It is measured in 1 laboratory test on BiomarkersLabs.com.
Secretory IgA is the principal mucosal antibody, secreted across the gut epithelium to bind pathogens and antigens at the mucosal surface. Faecal levels are taken to reflect mucosal humoral immune activity.
Faecal secretory IgA is interpreted as a marker of gut mucosal immune status, with low levels suggested to indicate reduced mucosal defence and high levels an active mucosal immune response. Its clinical interpretation is less standardised than that of calprotectin or elastase. # REVIEWER FLAG: Evidence base for clinical decisions on sIgA is limited — reviewer to confirm positioning.
Reference ranges vary by laboratory and assay platform. Interpret in context of the issuing laboratory's stated range.
1 test on BiomarkersLabs.com include this biomarker.
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