Biomarker Reference · Pathobionts
Pathobiont and pathogen detection (Pathobionts) is a clinical biomarker used in microbiome-gut assessment. Pathobionts are commensal organisms that can become pathogenic when the microbiome is disrupted or the mucosal barrier is immature. It is measured in 1 laboratory test on BiomarkersLabs.com.
Pathobionts are commensal organisms that can become pathogenic when the microbiome is disrupted or the mucosal barrier is immature. Clostridioides difficile, Klebsiella pneumoniae, and enteropathogenic E. coli may transiently colonise neonates but are normally outcompeted by beneficial commensals. Candida overgrowth occurs with antibiotic exposure or dysbiosis.
Detection and quantification of pathobionts inform the risk of infection, dysbiosis-associated inflammation, and need for clinical surveillance. Overgrowth of C. difficile or Klebsiella in the absence of protective Bifidobacterium is linked to antibiotic-associated diarrhoea, necrotising enterocolitis risk in preterm infants, and delayed immune maturation.
Reference ranges vary by laboratory and assay platform. Interpret in context of the issuing laboratory's stated range.
1 test on BiomarkersLabs.com include this biomarker.
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