What does the Progesterone (Saliva) test measure?

Why is Progesterone (Saliva) measured?

Salivary progesterone is used to assess luteal-phase progesterone and the oestrogen-to-progesterone balance in functional hormone assessment, and to monitor progesterone therapy. Because levels are highly cycle-dependent, collection timing is essential, and salivary measurement is sensitive to topical progesterone contamination.

Reference ranges

Standard reference

Cycle-, sex-, and method-specific salivary intervals # REVIEWER FLAG: Salivary progesterone intervals are proprietary and cycle-dependent — reviewer to confirm against the laboratory's current intervals.

Functional medicine optimal

Mid-luteal saliva progesterone above approximately 100 pg/mL is generally considered evidence of ovulation; higher values (150–300 pg/mL) are associated with robust luteal function. Post-menopausal women not on therapy typically show values below 20 pg/mL.

Units

pg/mL, nmol/L

Reference ranges vary by laboratory and assay platform. Interpret in context of the issuing laboratory's stated range.