What is the reference range for Serum Copper?

The standard reference range for Serum Copper is Approximately 70–140 µg/dL (11–22 µmol/L), age- and sex-specific.. Reference ranges vary by laboratory and assay platform — interpret in context of the issuing laboratory's stated range.

Which tests measure Serum Copper?

Serum Copper is measured in 1 test on BiomarkersLabs.com, including ADHD Ultimate Panel.

Biomarker Reference · Cu

What does the Serum Copper test measure?

Q: Why is Serum Copper measured?

Both deficiency and excess copper have been proposed to influence attention, mood, and behaviour. Some functional practitioners interpret elevated copper or a high copper:zinc ratio as a contributor to hyperactivity and anxiety, though robust clinical evidence for these associations in ADHD is lacking.

Serum Copper (Cu) is a clinical biomarker used in comprehensive-panels assessment. Copper is an essential cofactor for enzymes involved in neurotransmitter synthesis (dopamine beta-hydroxylase, tyrosinase), mitochondrial respiration, and antioxidant defence. It is measured in 1 laboratory test on BiomarkersLabs.com.

Reference Range: Approximately 70–140 µg/dL (11–22 µmol/L), age- and sex-specific.
Units: µg/dL, µmol/L
Measured In: 1 test
Category: —

Functional medicine optimalFunctional ranges vary widely; copper:zinc ratio thresholds (e.g., <1.0) are commonly cited but are not validated for ADHD diagnosis or management.

What is Serum Copper?

Copper is an essential cofactor for enzymes involved in neurotransmitter synthesis (dopamine beta-hydroxylase, tyrosinase), mitochondrial respiration, and antioxidant defence. Most circulating copper is bound to ceruloplasmin. Imbalances affect catecholamine production, iron metabolism, and oxidative stress pathways relevant to neuropsychiatric function.

Why is Serum Copper measured?

Both deficiency and excess copper have been proposed to influence attention, mood, and behaviour. Some functional practitioners interpret elevated copper or a high copper:zinc ratio as a contributor to hyperactivity and anxiety, though robust clinical evidence for these associations in ADHD is lacking.

Reference ranges

Standard reference: Approximately 70–140 µg/dL (11–22 µmol/L), age- and sex-specific.
Functional medicine optimal: Functional ranges vary widely; copper:zinc ratio thresholds (e.g., <1.0) are commonly cited but are not validated for ADHD diagnosis or management.
Units: µg/dL, µmol/L

Reference ranges vary by laboratory and assay platform. Interpret in context of the issuing laboratory's stated range.

Tests that measure Serum Copper

1 test on BiomarkersLabs.com include this biomarker.

BML-CHP-021Comprehensive

ADHD Ultimate Panel

Serum Copper reference range in this test: Approximately 70–140 µg/dL (11–22 µmol/L), age- and sex-specific.

Related clinical conditions

Related Biomarkers

Frequently measured alongside

Serum ZincZn1 test Serum MagnesiumMg1 test Serum FerritinFerritin1 test 25-Hydroxyvitamin D25(OH)D2 tests Omega-3 IndexO3I1 test HomocysteineHcy5 tests High-Sensitivity C-Reactive Proteinhs-CRP1 test Thyroid-Stimulating HormoneTSH1 test

Order tests measuring Serum Copper for your patients

Available exclusively to verified licensed healthcare practitioners. CLIA-certified laboratory results delivered to your secure portal.