Androstenedione

Description

The Menopause Hormone Panel from BiomarkersLabs.com is a comprehensive hormonal assessment for post-menopausal women — those who have experienced 12 consecutive months of amenorrhoea — and for women who have undergone surgical menopause. Menopause marks the permanent cessation of ovarian follicular activity and the sustained deficiency of oestradiol and progesterone that follows. In post-menopausal women, FSH rises markedly and persistently, oestradiol falls to very low levels, and both testosterone and DHEA-S decline significantly — producing the wide-ranging consequences of sex hormone deficiency that affect the cardiovascular, skeletal, neurological, genitourinary, and metabolic systems.

This panel provides the full hormonal picture required for post-menopausal assessment and HRT management — measuring FSH, LH, oestradiol, total testosterone, SHBG, and DHEA-S to characterise the complete sex hormone milieu and guide individualised treatment decisions. In women on HRT, the panel enables monitoring of oestradiol adequacy, free testosterone bioavailability via SHBG, and adrenal androgen support. In women not yet on HRT, the panel establishes the severity of hormonal deficiency and informs the case for treatment initiation. Results are CLIA-certified (USA) and IVDR-compliant (EU/UK), delivered to the practitioner portal within 3–5 business days.

What does the Menopause Hormone Panel measure?

FSH (Follicle Stimulating Hormone) — markedly elevated in post-menopausal women (typically >30–40 IU/L), confirming ovarian failure and menopausal status.

LH (Luteinising Hormone) — also elevated post-menopause; assessed alongside FSH.

Oestradiol (E2) — markedly suppressed in post-menopause. Measurement guides HRT dosing and oestrogen adequacy assessment in women on therapy.

Total Testosterone (female high-sensitivity assay) — declines in post-menopausal women. Low testosterone is associated with reduced libido, fatigue, and impaired quality of life. Guides testosterone replacement decisions.

SHBG (Sex Hormone-Binding Globulin) — elevated by oral oestrogen therapy; suppressed by transdermal or injectable routes. Essential for free testosterone interpretation in HRT context.

DHEA-S — adrenal androgen precursor, declining with age. Provides adrenal contribution to post-menopausal androgen pool.

Clinical indications

Menopausal status confirmation — biochemical confirmation of post-menopausal status in women with 12 months of amenorrhoea, particularly where this is unclear or where surgical history complicates clinical assessment.

HRT initiation hormonal baseline — comprehensive pre-treatment hormonal profile to guide oestrogen, progesterone, and testosterone dosing and provide reference values for future monitoring.

HRT monitoring and dose optimisation — periodic assessment of oestradiol, testosterone, and SHBG during HRT to confirm therapeutic adequacy, optimise dosing, and avoid over- or under-replacement.

Post-menopausal low libido and androgen deficiency — testosterone and DHEA-S measurement in post-menopausal women with hypoactive sexual desire disorder, fatigue, or reduced wellbeing to assess for androgen deficiency and guide testosterone therapy decisions.

Premature surgical menopause management — women who have undergone bilateral oophorectomy before natural menopause face acute hormonal deficiency; this panel characterises the hormonal status and guides HRT initiation.

Cardiovascular and bone health risk stratification — oestradiol deficiency is a major driver of post-menopausal cardiovascular risk and osteoporosis. Hormonal assessment contextualises these risks and supports preventive management decisions.

Sample type and collection

Blood (serum). No fasting required. Venepuncture at an approved collection site. Post-menopausal women can be tested on any day — no cycle-day timing applies. For women on HRT, samples should be taken at a standardised point relative to dosing schedule to ensure consistent monitoring comparisons.

Turnaround time

3–5 business days from specimen receipt.

Availability

USA · EU · UK · Canada

Compliance

CLIA Certified · IVDR Compliant · CE Marked · HIPAA Compliant · GDPR Compliant · PIPEDA Compliant

How to order

Register free at BiomarkersLabs.com. Licensed practitioners only. Pay per test — no subscription required. Results are delivered directly and securely to your practitioner portal and are never released directly to patients.