What is the reference range for Apolipoprotein A-1?

The standard reference range for Apolipoprotein A-1 is Approximately 100–200 mg/dL; lower limits differ by sex (men typically >120 mg/dL, women >140 mg/dL).. Reference ranges vary by laboratory and assay platform — interpret in context of the issuing laboratory's stated range.

Which tests measure Apolipoprotein A-1?

Apolipoprotein A-1 is measured in 1 test on BiomarkersLabs.com, including Apolipoprotein Evaluation (Apo-A-1, Apo-B, Lp(a)).

Biomarker Reference · Apo-A-1

What does the Apolipoprotein A-1 test measure?

Apolipoprotein A-1 (Apo-A-1) is a clinical biomarker used in cardiovascular assessment. Apolipoprotein A-1 is the principal structural and functional protein of high-density lipoprotein particles. It is measured in 1 laboratory test on BiomarkersLabs.com.

Reference Range: Approximately 100–200 mg/dL; lower limits differ by sex (men typically >120 mg/dL, women >140 mg/dL).
Units: mg/dL, g/L
Measured In: 1 test
Category: Cardiovascular

Functional medicine optimalGuidelines do not define universal optimal thresholds, but values >150 mg/dL in men and >160 mg/dL in women are associated with lower cardiovascular risk in epidemiological studies.

What is Apolipoprotein A-1?

Apolipoprotein A-1 is the principal structural and functional protein of high-density lipoprotein particles. It activates lecithin-cholesterol acyltransferase, which esterifies free cholesterol on the HDL surface, and serves as the ligand for hepatic HDL receptors that mediate reverse cholesterol transport. Each HDL particle carries multiple Apo-A-1 molecules, making Apo-A-1 concentration a direct measure of HDL particle number rather than cholesterol content.

Why is Apolipoprotein A-1 measured?

Low Apo-A-1 reflects reduced HDL particle number and impaired reverse cholesterol transport, conferring elevated cardiovascular risk even when HDL-cholesterol appears adequate. Apo-A-1 is a stronger inverse predictor of coronary events than HDL-C in many cohorts and is particularly useful when HDL particle size or composition is altered by diabetes, hypertriglyceridaemia, or inflammatory states.

Reference ranges

Standard reference: Approximately 100–200 mg/dL; lower limits differ by sex (men typically >120 mg/dL, women >140 mg/dL).
Functional medicine optimal: Guidelines do not define universal optimal thresholds, but values >150 mg/dL in men and >160 mg/dL in women are associated with lower cardiovascular risk in epidemiological studies.
Units: mg/dL, g/L

Reference ranges vary by laboratory and assay platform. Interpret in context of the issuing laboratory's stated range.

Tests that measure Apolipoprotein A-1

1 test on BiomarkersLabs.com include this biomarker.

BML-CAR-050Comprehensive

Apolipoprotein Evaluation (Apo-A-1, Apo-B, Lp(a))

Apolipoprotein A-1 reference range in this test: Approximately 100–200 mg/dL; lower limits differ by sex (men typically >120 mg/dL, women >140 mg/dL).

Related clinical conditions

Related Biomarkers

Frequently measured alongside

Apolipoprotein BApo-B2 tests Lipoprotein(a)Lp(a)2 tests Apo-B/Apo-A-1 RatioApo-B/A-11 test

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