What is the reference range for Cortisol (Dried Urine, Diurnal Series, LCMS)?

The standard reference range for Cortisol (Dried Urine, Diurnal Series, LCMS) is Time-of-day-dependent; morning highest, midnight lowest.. Reference ranges vary by laboratory and assay platform — interpret in context of the issuing laboratory's stated range.

Which tests measure Cortisol (Dried Urine, Diurnal Series, LCMS)?

Cortisol (Dried Urine, Diurnal Series, LCMS) is measured in 1 test on BiomarkersLabs.com, including Blood Spot Thyroids + Dried Urine GCMS Hormone Metabolites and LCMS Diurnal Hormones I.

Biomarker Reference · Cortisol

What does the Cortisol (Dried Urine, Diurnal Series, LCMS) test measure?

Cortisol (Dried Urine, Diurnal Series, LCMS) (Cortisol) is a clinical biomarker used in thyroid-endocrine assessment. Liquid chromatography–mass spectrometry quantifies free cortisol in dried urine across multiple timed collections (typically morning, afternoon, evening, night), mapping the diurnal rhythm. It is measured in 1 laboratory test on BiomarkersLabs.com.

Reference Range: Time-of-day-dependent; morning highest, midnight lowest.
Units: ng/mg creatinine
Measured In: 1 test
Category: Thyroid

Functional medicine optimalHealthy rhythm shows morning peak declining to night nadir; functional ranges are method-specific.

What is Cortisol (Dried Urine, Diurnal Series, LCMS)?

Liquid chromatography–mass spectrometry quantifies free cortisol in dried urine across multiple timed collections (typically morning, afternoon, evening, night), mapping the diurnal rhythm. This method avoids cross-reactivity with cortisone and synthetic steroids.

Why is Cortisol (Dried Urine, Diurnal Series, LCMS) measured?

Diurnal cortisol profiles detect loss of rhythm (flattened or inverted curves in chronic stress or Cushing's), identify nocturnal elevations, and guide functional adrenal-support interventions. Patterns matter more than single values.

Reference ranges

Standard reference: Time-of-day-dependent; morning highest, midnight lowest.
Functional medicine optimal: Healthy rhythm shows morning peak declining to night nadir; functional ranges are method-specific.
Units: ng/mg creatinine

Reference ranges vary by laboratory and assay platform. Interpret in context of the issuing laboratory's stated range.

Tests that measure Cortisol (Dried Urine, Diurnal Series, LCMS)

1 test on BiomarkersLabs.com include this biomarker.

BML-THY-033Comprehensive

Blood Spot Thyroids + Dried Urine GCMS Hormone Metabolites and LCMS Diurnal Hormones I

Cortisol (Dried Urine, Diurnal Series, LCMS) reference range in this test: Time-of-day-dependent; morning highest, midnight lowest.

Related clinical conditions

Related Biomarkers

Frequently measured alongside

Thyroid-Stimulating HormoneTSH5 tests Free ThyroxineFT45 tests Free TriiodothyronineFT35 tests Thyroid Peroxidase Antibodies (dried blood spot)TPOAb3 tests Thyroglobulin Antibodies (Dried Blood Spot)Tg Ab2 tests Oestradiol (Dried Urine, GCMS)E₂1 test Progesterone (Dried Urine, GCMS)P₄1 test Testosterone (Dried Urine, GCMS)T1 test

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