What is the reference range for Thyroid Peroxidase Antibodies (dried blood spot)?

The standard reference range for Thyroid Peroxidase Antibodies (dried blood spot) is Typically <35 IU/mL; manufacturer-specific cut-offs apply.. Reference ranges vary by laboratory and assay platform — interpret in context of the issuing laboratory's stated range.

Which tests measure Thyroid Peroxidase Antibodies (dried blood spot)?

Thyroid Peroxidase Antibodies (dried blood spot) is measured in 3 tests on BiomarkersLabs.com, including Blood Spot Thyroids + Dried Urine GCMS Estrogen Hormone Metabolites, Blood Spot Thyroids + Dried Urine GCMS Hormone Metabolites and LCMS Diurnal Hormones I, Blood Spot Thyroids + Dried Urine ICPMS Iodine.

Biomarker Reference · TPOAb

What does the Thyroid Peroxidase Antibodies (dried blood spot) test measure?

Q: What is Thyroid Peroxidase Antibodies (dried blood spot)?

Thyroid peroxidase antibodies are immunoglobulins directed against the enzyme thyroid peroxidase, which catalyses iodination of tyrosine residues on thyroglobulin. TPOAb is the hallmark of autoimmune thyroid disease, particularly Hashimoto thyroiditis, and reflects T-cell-mediated autoimmune attack on thyroid follicles.

Q: Why is Thyroid Peroxidase Antibodies (dried blood spot) measured?

Positive TPOAb confirms autoimmune aetiology in hypothyroidism, stratifies risk in subclinical disease, and may influence reproductive and obstetric management. In a thyroid-plus-oestrogen panel, TPOAb identifies patients whose thyroid dysfunction may fluctuate and whose immune dysregulation can affect sex-steroid pathways.

Q: Which tests measure Thyroid Peroxidase Antibodies (dried blood spot)?

Thyroid Peroxidase Antibodies (dried blood spot) is measured in 3 tests on BiomarkersLabs.com, including Blood Spot Thyroids + Dried Urine GCMS Estrogen Hormone Metabolites, Blood Spot Thyroids + Dried Urine GCMS Hormone Metabolites and LCMS Diurnal Hormones I, Blood Spot Thyroids + Dried Urine ICPMS Iodine.

Thyroid Peroxidase Antibodies (dried blood spot) (TPOAb) is a clinical biomarker used in thyroid-endocrine assessment. Thyroid peroxidase antibodies are immunoglobulins directed against the enzyme thyroid peroxidase, which catalyses iodination of tyrosine residues on thyroglobulin. It is measured in 3 laboratory tests on BiomarkersLabs.com.

Reference Range: Typically <35 IU/mL; manufacturer-specific cut-offs apply.
Units: IU/mL
Measured In: 3 tests
Category: Thyroid

Functional medicine optimalNegative; trends may inform disease activity, though titre does not correlate tightly with severity.

What is Thyroid Peroxidase Antibodies (dried blood spot)?

Thyroid peroxidase antibodies are immunoglobulins directed against the enzyme thyroid peroxidase, which catalyses iodination of tyrosine residues on thyroglobulin. TPOAb is the hallmark of autoimmune thyroid disease, particularly Hashimoto thyroiditis, and reflects T-cell-mediated autoimmune attack on thyroid follicles.

Why is Thyroid Peroxidase Antibodies (dried blood spot) measured?

Positive TPOAb confirms autoimmune aetiology in hypothyroidism, stratifies risk in subclinical disease, and may influence reproductive and obstetric management. In a thyroid-plus-oestrogen panel, TPOAb identifies patients whose thyroid dysfunction may fluctuate and whose immune dysregulation can affect sex-steroid pathways.

Reference ranges

Standard reference: Typically <35 IU/mL; manufacturer-specific cut-offs apply.
Functional medicine optimal: Negative; trends may inform disease activity, though titre does not correlate tightly with severity.
Units: IU/mL

Reference ranges vary by laboratory and assay platform. Interpret in context of the issuing laboratory's stated range.

Tests that measure Thyroid Peroxidase Antibodies (dried blood spot)

3 tests on BiomarkersLabs.com include this biomarker.

BML-THY-032Comprehensive

Blood Spot Thyroids + Dried Urine GCMS Estrogen Hormone Metabolites

Thyroid Peroxidase Antibodies (dried blood spot) reference range in this test: Typically <35 IU/mL; manufacturer-specific cut-offs apply.

BML-THY-033Comprehensive

Blood Spot Thyroids + Dried Urine GCMS Hormone Metabolites and LCMS Diurnal Hormones I

Thyroid Peroxidase Antibodies (dried blood spot) reference range in this test: Negative is typically <35 IU/mL; assay-dependent.

BML-THY-035Comprehensive

Blood Spot Thyroids + Dried Urine ICPMS Iodine

Thyroid Peroxidase Antibodies (dried blood spot) reference range in this test: <35 IU/mL (method-specific); positive above threshold.

Related clinical conditions

Related Biomarkers

Frequently measured alongside

Thyroid-Stimulating HormoneTSH5 tests Free ThyroxineFT45 tests Free TriiodothyronineFT35 tests Thyroglobulin Antibodies (Dried Blood Spot)Tg Ab2 tests Estrone (dried urine, GCMS)E11 test Estradiol (dried urine, GCMS)E21 test Estriol (dried urine, GCMS)E31 test 2-Hydroxyestrone (dried urine, GCMS)2-OHE11 test

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