Biomarker Reference · Tg Ab
Thyroglobulin Antibodies (Dried Blood Spot) (Tg Ab) is a clinical biomarker used in thyroid-endocrine assessment. Thyroglobulin antibodies are directed against thyroglobulin, the iodinated glycoprotein scaffold for thyroid hormone synthesis. It is measured in 2 laboratory tests on BiomarkersLabs.com.
Thyroglobulin antibodies are directed against thyroglobulin, the iodinated glycoprotein scaffold for thyroid hormone synthesis. They are present in a smaller proportion of autoimmune thyroid disease cases than TPOAb, often coexist with TPOAb, and can interfere with serum thyroglobulin measurements used in thyroid cancer surveillance.
Positive TgAb identifies autoimmune thyroid disease when TPOAb is negative, and its presence must be noted when interpreting thyroglobulin results in post-thyroidectomy monitoring. In functional practice, dual positivity (TPOAb and TgAb) signals a robust autoimmune process.
Reference ranges vary by laboratory and assay platform. Interpret in context of the issuing laboratory's stated range.
2 tests on BiomarkersLabs.com include this biomarker.
Thyroglobulin Antibodies (Dried Blood Spot) reference range in this test: Negative is typically <40 IU/mL; assay-dependent.
Thyroglobulin Antibodies (Dried Blood Spot) reference range in this test: <40 IU/mL (method-specific); positive above threshold.
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