What does the Detoxification and Phase II Markers test measure?

Why is Detoxification and Phase II Markers measured?

These markers are used in functional medicine to assess hepatic detoxification capacity and oxidative stress. Low sulfate or high pyroglutamate may prompt supplementation with sulphur amino acids, N-acetylcysteine, or glycine. Elevated orotate is a functional clue to urea cycle stress or arginine insufficiency, though primary urea cycle defects present with hyperammonaemia.

Reference ranges

Standard reference

Laboratory-specific functional ranges

Functional medicine optimal

Functional optimal ranges are assay-specific and reflect subclinical stress; they are exploratory tools rather than diagnostic thresholds.

Units

mmol/mol creatinine

Reference ranges vary by laboratory and assay platform. Interpret in context of the issuing laboratory's stated range.