Biomarker Reference · F:B ratio
Firmicutes-to-Bacteroidetes Ratio (derived) (F:B ratio) is a clinical biomarker used in microbiome-gut assessment. The Firmicutes-to-Bacteroidetes ratio is a derived summary of the two phyla that typically dominate the adult gut community. It is measured in 1 laboratory test on BiomarkersLabs.com.
The Firmicutes-to-Bacteroidetes ratio is a derived summary of the two phyla that typically dominate the adult gut community. It was popularised by early sequencing studies of body weight and diet, and it shifts with fibre intake, geography, and methodology. It is a coarse compositional descriptor rather than a measure of any single function.
Although widely reported, the F:B ratio has limited and inconsistent clinical validity: studies disagree on its direction of association with obesity and metabolic outcomes, and it is strongly influenced by sequencing method and taxonomic database. It is retained here as a familiar descriptor but should carry little diagnostic weight.
Reference ranges vary by laboratory and assay platform. Interpret in context of the issuing laboratory's stated range.
1 test on BiomarkersLabs.com include this biomarker.
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