What is the reference range for Immunoglobulin G?

The standard reference range for Immunoglobulin G is Approximately 7–16 g/L (700–1600 mg/dL), age- and assay-specific.. Reference ranges vary by laboratory and assay platform — interpret in context of the issuing laboratory's stated range.

Which tests measure Immunoglobulin G?

Immunoglobulin G is measured in 1 test on BiomarkersLabs.com, including Autoimmune Liver Disease Panel.

Biomarker Reference · IgG

What does the Immunoglobulin G test measure?

Immunoglobulin G (IgG) is a clinical biomarker used in gastrointestinal assessment. Immunoglobulin G is the most abundant serum antibody class, mediating long-term humoral immunity and placental transfer of maternal antibodies. It is measured in 1 laboratory test on BiomarkersLabs.com.

Reference Range: Approximately 7–16 g/L (700–1600 mg/dL), age- and assay-specific.
Units: g/L, mg/dL
Measured In: 1 test
Category: Gastrointestinal

Functional medicine optimalWithin the age-specific reference range; marked elevation (>1.5× upper limit) in the setting of hepatocellular injury and positive autoantibodies suggests autoimmune hepatitis.

What is Immunoglobulin G?

Immunoglobulin G is the most abundant serum antibody class, mediating long-term humoral immunity and placental transfer of maternal antibodies. It is produced by plasma cells in response to antigen stimulation and its serum concentration reflects the integrated activity of the adaptive immune system. Polyclonal hypergammaglobulinaemia — a diffuse increase in IgG — occurs when chronic antigen exposure or loss of tolerance drives sustained B-cell activation.

Why is Immunoglobulin G measured?

Elevated IgG is a hallmark of autoimmune hepatitis, often exceeding 1.5 times the upper limit of normal and occasionally reaching 20–30 g/L. The degree of elevation correlates loosely with histological activity and is one component of the simplified diagnostic criteria for AIH. IgG also rises in chronic viral hepatitis, cirrhosis, and some lymphoproliferative disorders, so it must be interpreted alongside liver-specific autoantibodies, liver biochemistry, and histology. A fall in IgG during treatment signals response to immunosuppression.

Reference ranges

Standard reference: Approximately 7–16 g/L (700–1600 mg/dL), age- and assay-specific.
Functional medicine optimal: Within the age-specific reference range; marked elevation (>1.5× upper limit) in the setting of hepatocellular injury and positive autoantibodies suggests autoimmune hepatitis.
Units: g/L, mg/dL

Reference ranges vary by laboratory and assay platform. Interpret in context of the issuing laboratory's stated range.

Tests that measure Immunoglobulin G

1 test on BiomarkersLabs.com include this biomarker.

BML-GAS-061Comprehensive

Autoimmune Liver Disease Panel

Immunoglobulin G reference range in this test: Approximately 7–16 g/L (700–1600 mg/dL), age- and assay-specific.

Related clinical conditions

Related Biomarkers

Frequently measured alongside

Anti-Mitochondrial AntibodiesAMA1 test Anti-Smooth Muscle AntibodiesASMA1 test Antinuclear AntibodiesANA1 test Anti-Liver-Kidney Microsomal AntibodiesAnti-LKM1 test Anti-Soluble Liver Antigen / Liver-Pancreas AntibodiesAnti-SLA/LP1 test

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