Biomarker Reference · B6
Intracellular Vitamin B6 (Pyridoxine) (B6) is a clinical biomarker used in comprehensive-panels assessment. Pyridoxal-5'-phosphate (PLP) is the active form of vitamin B6 and serves as a cofactor for more than 100 enzymes, including those in amino-acid metabolism, neurotransmitter synthesis, haemoglobin synthesis, and homocysteine remethylation. It is measured in 2 laboratory tests on BiomarkersLabs.com.
Pyridoxal-5'-phosphate (PLP) is the active form of vitamin B6 and serves as a cofactor for more than 100 enzymes, including those in amino-acid metabolism, neurotransmitter synthesis, haemoglobin synthesis, and homocysteine remethylation. Intracellular PLP in lymphocytes is intended to reflect tissue sufficiency.
Vitamin B6 deficiency can cause microcytic anaemia, peripheral neuropathy, and depression. Functional intracellular testing is used to identify marginal deficiency in patients with normal plasma PLP, particularly those with chronic inflammation or alcohol use, which can impair B6 status independently of intake.
Reference ranges vary by laboratory and assay platform. Interpret in context of the issuing laboratory's stated range.
2 tests on BiomarkersLabs.com include this biomarker.
Intracellular Vitamin B6 (Pyridoxine) reference range in this test: Laboratory-specific functional range.
Intracellular Vitamin B6 (Pyridoxine) reference range in this test: Laboratory-specific functional performance scale.
Related Biomarkers
Available exclusively to verified licensed healthcare practitioners. CLIA-certified laboratory results delivered to your secure portal.
Create Free Account