Biomarker Reference · 25(OH)D
Intracellular Vitamin D (25-Hydroxyvitamin D) (25(OH)D) is a clinical biomarker used in comprehensive-panels assessment. Serum 25-hydroxyvitamin D is the established biomarker of vitamin D status, reflecting hepatic hydroxylation of dietary and cutaneous cholecalciferol. It is measured in 2 laboratory tests on BiomarkersLabs.com.
Serum 25-hydroxyvitamin D is the established biomarker of vitamin D status, reflecting hepatic hydroxylation of dietary and cutaneous cholecalciferol. Intracellular 25(OH)D measurement in lymphocytes is proposed to reflect cellular uptake and activation, though its correlation with serum 25(OH)D and clinical outcomes is not well characterised.
Vitamin D is essential for calcium homeostasis and bone health and has immunomodulatory effects. Intracellular assay is marketed to identify cellular insufficiency despite adequate serum levels, a concept that remains exploratory and not endorsed by endocrine or bone-health guidelines.
Reference ranges vary by laboratory and assay platform. Interpret in context of the issuing laboratory's stated range.
2 tests on BiomarkersLabs.com include this biomarker.
Intracellular Vitamin D (25-Hydroxyvitamin D) reference range in this test: Laboratory-specific functional range.
Intracellular Vitamin D (25-Hydroxyvitamin D) reference range in this test: Laboratory-specific functional performance scale.
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