Biomarker Reference · Pb
Lead (Blood) (Pb) is a clinical biomarker used in heavy-metals-toxicology assessment. Lead is a non-essential heavy metal with no physiological role. It is measured in 3 laboratory tests on BiomarkersLabs.com.
Lead is a non-essential heavy metal with no physiological role. Whole-blood lead reflects both recent exposure and a component of release from bone stores during remodelling. It is a neurotoxin, nephrotoxin, and haematotoxin; even low-level chronic exposure impairs cognitive development in children and is associated with hypertension and renal impairment in adults. Lead binds to sulphydryl groups on proteins and interferes with enzymes in haem synthesis.
Blood lead is the standard marker for recent lead exposure and is used to screen occupational and environmental exposure, guide chelation decisions, and monitor workers in lead industries. Chronic low-level exposure is associated with neurodevelopmental deficits in children and cardiovascular, renal, and neurocognitive effects in adults. No safe threshold has been established for children.
Reference ranges vary by laboratory and assay platform. Interpret in context of the issuing laboratory's stated range.
3 tests on BiomarkersLabs.com include this biomarker.
Lead (Blood) reference range in this test: <3.5 µg/dL (adult); paediatric reference limits lower.
Lead (Blood) reference range in this test: ZRT laboratory-specific; public health reference <5 µg/dL (CDC), no known safe threshold.
Lead (Blood) reference range in this test: Background population <5 µg/dL; occupational thresholds and regulatory limits vary by jurisdiction.
Available exclusively to verified licensed healthcare practitioners. CLIA-certified laboratory results delivered to your secure portal.
Create Free Account