Which tests measure Oestradiol (E2)?

Oestradiol (E2) is measured in 1 test on BiomarkersLabs.com, including Female Quick Check Basic Panel.

Biomarker Reference · E2

What does the Oestradiol (E2) test measure?

Q: Why is Oestradiol (E2) measured?

Oestradiol is essential context for interpreting FSH, since an elevated early-follicular oestradiol suppresses FSH and can conceal diminished ovarian reserve — the two must always be read together. It confirms ovarian activity, assists in distinguishing menopausal status, and is central to the assessment of amenorrhoea. Immunoassay performance is limited at the low concentrations characteristic of postmenopausal women, where mass spectrometry provides better reliability.

Q: What is the reference range for Oestradiol (E2)?

The standard reference range for Oestradiol (E2) is Cycle-phase dependent — early follicular approximately 20–80 pg/mL, rising to a pre-ovulatory peak; postmenopausal typically <30 pg/mL. Reference ranges vary by laboratory and assay platform — interpret in context of the issuing laboratory's stated range.

Oestradiol (E2) (E2) is a clinical biomarker used in female-hormones assessment. Oestradiol is the principal circulating oestrogen, produced predominantly by ovarian granulosa cells under FSH stimulation, with smaller contributions from peripheral aromatisation of androgens in adipose tissue. It is measured in 1 laboratory test on BiomarkersLabs.com.

Reference Range: Cycle-phase dependent — early follicular approximately 20–80 pg/mL, rising to a pre-ovulatory peak; postmenopausal typically <30 pg/mL
Units: pg/mL, pmol/L
Measured In: 1 test
Category: Female Hormones

Functional medicine optimalNot applicable — interpreted against cycle-phase-specific intervals rather than an independent target

What is Oestradiol (E2)?

Oestradiol is the principal circulating oestrogen, produced predominantly by ovarian granulosa cells under FSH stimulation, with smaller contributions from peripheral aromatisation of androgens in adipose tissue. It rises through the follicular phase to a pre-ovulatory peak that triggers the LH surge, falls after ovulation, and rises again in the luteal phase. Most circulating oestradiol is bound to sex hormone binding globulin and albumin.

Why is Oestradiol (E2) measured?

Oestradiol is essential context for interpreting FSH, since an elevated early-follicular oestradiol suppresses FSH and can conceal diminished ovarian reserve — the two must always be read together. It confirms ovarian activity, assists in distinguishing menopausal status, and is central to the assessment of amenorrhoea. Immunoassay performance is limited at the low concentrations characteristic of postmenopausal women, where mass spectrometry provides better reliability.

Reference ranges

Standard reference: Cycle-phase dependent — early follicular approximately 20–80 pg/mL, rising to a pre-ovulatory peak; postmenopausal typically <30 pg/mL
Functional medicine optimal: Not applicable — interpreted against cycle-phase-specific intervals rather than an independent target
Units: pg/mL, pmol/L

Reference ranges vary by laboratory and assay platform. Interpret in context of the issuing laboratory's stated range.

Tests that measure Oestradiol (E2)

1 test on BiomarkersLabs.com include this biomarker.

BML-HRF-007Comprehensive

Female Quick Check Basic Panel

Oestradiol (E2) reference range in this test: Cycle-phase dependent — early follicular approximately 20–80 pg/mL, rising to a pre-ovulatory peak; postmenopausal typically <30 pg/mL

Related clinical conditions

Related Biomarkers

Frequently measured alongside

Follicle Stimulating HormoneFSH1 test Luteinising HormoneLH1 test ProlactinPRL1 test Thyroid Stimulating HormoneTSH1 test Testosterone, TotalTotal T1 test

Order tests measuring Oestradiol (E2) for your patients

Available exclusively to verified licensed healthcare practitioners. CLIA-certified laboratory results delivered to your secure portal.