What is the reference range for 4-Methoxyestradiol (dried urine, GCMS)?

The standard reference range for 4-Methoxyestradiol (dried urine, GCMS) is Very low; laboratory-specific.. Reference ranges vary by laboratory and assay platform — interpret in context of the issuing laboratory's stated range.

Which tests measure 4-Methoxyestradiol (dried urine, GCMS)?

4-Methoxyestradiol (dried urine, GCMS) is measured in 1 test on BiomarkersLabs.com, including Blood Spot Thyroids + Dried Urine GCMS Estrogen Hormone Metabolites.

Biomarker Reference · 4-MeOE2

What does the 4-Methoxyestradiol (dried urine, GCMS) test measure?

4-Methoxyestradiol (dried urine, GCMS) (4-MeOE2) is a clinical biomarker used in thyroid-endocrine assessment. 4-Methoxyestradiol is the methylated product of 4-hydroxyestradiol, completing the 4-pathway detoxification cascade. It is measured in 1 laboratory test on BiomarkersLabs.com.

Reference Range: Very low; laboratory-specific.
Units: ng/mg creatinine
Measured In: 1 test
Category: Thyroid

Functional medicine optimalDetectable levels indicate functional methylation of 4-pathway catechols.

What is 4-Methoxyestradiol (dried urine, GCMS)?

4-Methoxyestradiol is the methylated product of 4-hydroxyestradiol, completing the 4-pathway detoxification cascade.

Why is 4-Methoxyestradiol (dried urine, GCMS) measured?

4-MeOE2 is measured to assess the completeness of 4-hydroxy metabolite clearance and is interpreted alongside 4-MeOE1 in the aggregate methylation picture.

Reference ranges

Standard reference: Very low; laboratory-specific.
Functional medicine optimal: Detectable levels indicate functional methylation of 4-pathway catechols.
Units: ng/mg creatinine

Reference ranges vary by laboratory and assay platform. Interpret in context of the issuing laboratory's stated range.

Tests that measure 4-Methoxyestradiol (dried urine, GCMS)

1 test on BiomarkersLabs.com include this biomarker.

BML-THY-032Comprehensive

Blood Spot Thyroids + Dried Urine GCMS Estrogen Hormone Metabolites

4-Methoxyestradiol (dried urine, GCMS) reference range in this test: Very low; laboratory-specific.

Related clinical conditions

Related Biomarkers

Frequently measured alongside

Thyroid-Stimulating HormoneTSH5 tests Free ThyroxineFT45 tests Free TriiodothyronineFT35 tests Thyroid Peroxidase Antibodies (dried blood spot)TPOAb3 tests Estrone (dried urine, GCMS)E11 test Estradiol (dried urine, GCMS)E21 test Estriol (dried urine, GCMS)E31 test 2-Hydroxyestrone (dried urine, GCMS)2-OHE11 test

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