What is the reference range for 4-Hydroxyestradiol (dried urine, GCMS)?

The standard reference range for 4-Hydroxyestradiol (dried urine, GCMS) is Very low; method- and laboratory-specific.. Reference ranges vary by laboratory and assay platform — interpret in context of the issuing laboratory's stated range.

Which tests measure 4-Hydroxyestradiol (dried urine, GCMS)?

4-Hydroxyestradiol (dried urine, GCMS) is measured in 1 test on BiomarkersLabs.com, including Blood Spot Thyroids + Dried Urine GCMS Estrogen Hormone Metabolites.

Biomarker Reference · 4-OHE2

What does the 4-Hydroxyestradiol (dried urine, GCMS) test measure?

4-Hydroxyestradiol (dried urine, GCMS) (4-OHE2) is a clinical biomarker used in thyroid-endocrine assessment. 4-Hydroxyestradiol is the 4-hydroxylated derivative of estradiol and shares the potentially genotoxic redox profile of 4-OHE1. It is measured in 1 laboratory test on BiomarkersLabs.com.

Reference Range: Very low; method- and laboratory-specific.
Units: ng/mg creatinine
Measured In: 1 test
Category: Thyroid

Functional medicine optimalMinimal detectable level is considered preferable.

What is 4-Hydroxyestradiol (dried urine, GCMS)?

4-Hydroxyestradiol is the 4-hydroxylated derivative of estradiol and shares the potentially genotoxic redox profile of 4-OHE1. It is present at lower concentrations than the estrone metabolites.

Why is 4-Hydroxyestradiol (dried urine, GCMS) measured?

4-OHE2 is measured to complete the 4-hydroxylation picture and is summed with 4-OHE1 when calculating pathway ratios. Its redox potential makes it a marker of interest in oxidative-stress and cancer-risk models.

Reference ranges

Standard reference: Very low; method- and laboratory-specific.
Functional medicine optimal: Minimal detectable level is considered preferable.
Units: ng/mg creatinine

Reference ranges vary by laboratory and assay platform. Interpret in context of the issuing laboratory's stated range.

Tests that measure 4-Hydroxyestradiol (dried urine, GCMS)

1 test on BiomarkersLabs.com include this biomarker.

BML-THY-032Comprehensive

Blood Spot Thyroids + Dried Urine GCMS Estrogen Hormone Metabolites

4-Hydroxyestradiol (dried urine, GCMS) reference range in this test: Very low; method- and laboratory-specific.

Related clinical conditions

Related Biomarkers

Frequently measured alongside

Thyroid-Stimulating HormoneTSH5 tests Free ThyroxineFT45 tests Free TriiodothyronineFT35 tests Thyroid Peroxidase Antibodies (dried blood spot)TPOAb3 tests Estrone (dried urine, GCMS)E11 test Estradiol (dried urine, GCMS)E21 test Estriol (dried urine, GCMS)E31 test 2-Hydroxyestrone (dried urine, GCMS)2-OHE11 test

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