What is the reference range for Anti-Saccharomyces cerevisiae IgA?

The standard reference range for Anti-Saccharomyces cerevisiae IgA is <25 EU/mL negative; ≥25 EU/mL positive.. Reference ranges vary by laboratory and assay platform — interpret in context of the issuing laboratory's stated range.

Which tests measure Anti-Saccharomyces cerevisiae IgA?

Anti-Saccharomyces cerevisiae IgA is measured in 1 test on BiomarkersLabs.com, including Add-On Celiac, IBS, and Crohn's Assay (CICA).

Biomarker Reference · ASCA IgA

What does the Anti-Saccharomyces cerevisiae IgA test measure?

Q: What is Anti-Saccharomyces cerevisiae IgA?

Like ASCA IgG, ASCA IgA reflects mucosal immune recognition of yeast mannans. The two isotypes often appear together, and dual positivity strengthens the association with Crohn's disease. IgA isotypes are particularly relevant at mucosal surfaces, where secretory IgA dominates local immunity.

Q: Why is Anti-Saccharomyces cerevisiae IgA measured?

ASCA IgA adds incremental diagnostic value when interpreted alongside ASCA IgG. Dual positivity (both IgG and IgA) has higher specificity for Crohn's disease than either alone, and the combination with negative pANCA further favours Crohn's over ulcerative colitis.

Q: Which tests measure Anti-Saccharomyces cerevisiae IgA?

Anti-Saccharomyces cerevisiae IgA is measured in 1 test on BiomarkersLabs.com, including Add-On Celiac, IBS, and Crohn's Assay (CICA).

Anti-Saccharomyces cerevisiae IgA (ASCA IgA) is a clinical biomarker used in gastrointestinal assessment. Like ASCA IgG, ASCA IgA reflects mucosal immune recognition of yeast mannans. It is measured in 1 laboratory test on BiomarkersLabs.com.

Reference Range: <25 EU/mL negative; ≥25 EU/mL positive.
Units: EU/mL
Measured In: 1 test
Category: Gastrointestinal

Functional medicine optimalNegative (<25 EU/mL) in the absence of Crohn's disease or other conditions with heightened anti-yeast immunity.

What is Anti-Saccharomyces cerevisiae IgA?

Like ASCA IgG, ASCA IgA reflects mucosal immune recognition of yeast mannans. The two isotypes often appear together, and dual positivity strengthens the association with Crohn's disease. IgA isotypes are particularly relevant at mucosal surfaces, where secretory IgA dominates local immunity.

Why is Anti-Saccharomyces cerevisiae IgA measured?

ASCA IgA adds incremental diagnostic value when interpreted alongside ASCA IgG. Dual positivity (both IgG and IgA) has higher specificity for Crohn's disease than either alone, and the combination with negative pANCA further favours Crohn's over ulcerative colitis.

Reference ranges

Standard reference: <25 EU/mL negative; ≥25 EU/mL positive.
Functional medicine optimal: Negative (<25 EU/mL) in the absence of Crohn's disease or other conditions with heightened anti-yeast immunity.
Units: EU/mL

Reference ranges vary by laboratory and assay platform. Interpret in context of the issuing laboratory's stated range.

Tests that measure Anti-Saccharomyces cerevisiae IgA

1 test on BiomarkersLabs.com include this biomarker.

BML-GAS-053Comprehensive

Add-On Celiac, IBS, and Crohn's Assay (CICA)

Anti-Saccharomyces cerevisiae IgA reference range in this test: <25 EU/mL negative; ≥25 EU/mL positive.

Related clinical conditions

Related Biomarkers

Frequently measured alongside

Anti-Tissue Transglutaminase IgGanti-tTG IgG1 test Anti-Tissue Transglutaminase IgAanti-tTG IgA1 test Anti-Saccharomyces cerevisiae IgGASCA IgG1 test Anti-CBir1 Flagellin IgGanti-CBir11 test

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